Segal DJ - Search Results

1

Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain.

Bailus BJ, Pyles B, McAlister MM, O'Geen H, Lockwood SH, Adams AN, Nguyen JT, Yu A, Berman RF, Segal DJ. Bailus BJ, et al. Among authors: segal dj. Mol Ther. 2016 Mar;24(3):548-55. doi: 10.1038/mt.2015.236. Epub 2016 Jan 4. Mol Ther. 2016. PMID: 26727042 Free PMC article.

2

Designing transcription factor architectures for drug discovery.

Blancafort P, Segal DJ, Barbas CF 3rd. Blancafort P, et al. Among authors: segal dj. Mol Pharmacol. 2004 Dec;66(6):1361-71. doi: 10.1124/mol.104.002758. Epub 2004 Aug 31. Mol Pharmacol. 2004. PMID: 15340042 Review.

3

The generation of zinc finger proteins by modular assembly.

Bhakta MS, Segal DJ. Bhakta MS, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:3-30. doi: 10.1007/978-1-60761-753-2_1. Methods Mol Biol. 2010. PMID: 20680825 Free PMC article.

4

Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER).

Porter JR, Lockwood SH, Segal DJ, Ghosh I. Porter JR, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:365-82. doi: 10.1007/978-1-60761-753-2_23. Methods Mol Biol. 2010. PMID: 20680847

5

Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.

Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB. Meier JL, et al. Among authors: segal dj. J Am Chem Soc. 2012 Oct 24;134(42):17814-22. doi: 10.1021/ja308888c. Epub 2012 Oct 10. J Am Chem Soc. 2012. PMID: 23013524 Free PMC article.

6

Highly active zinc-finger nucleases by extended modular assembly.

Bhakta MS, Henry IM, Ousterout DG, Das KT, Lockwood SH, Meckler JF, Wallen MC, Zykovich A, Yu Y, Leo H, Xu L, Gersbach CA, Segal DJ. Bhakta MS, et al. Among authors: segal dj. Genome Res. 2013 Mar;23(3):530-8. doi: 10.1101/gr.143693.112. Epub 2012 Dec 5. Genome Res. 2013. PMID: 23222846 Free PMC article.

7

Quantitative analysis of TALE-DNA interactions suggests polarity effects.

Meckler JF, Bhakta MS, Kim MS, Ovadia R, Habrian CH, Zykovich A, Yu A, Lockwood SH, Morbitzer R, Elsäesser J, Lahaye T, Segal DJ, Baldwin EP. Meckler JF, et al. Among authors: segal dj. Nucleic Acids Res. 2013 Apr;41(7):4118-28. doi: 10.1093/nar/gkt085. Epub 2013 Feb 13. Nucleic Acids Res. 2013. PMID: 23408851 Free PMC article.

8

The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders.

Bailus BJ, Segal DJ. Bailus BJ, et al. Among authors: segal dj. BMC Neurosci. 2014 Jun 19;15:76. doi: 10.1186/1471-2202-15-76. BMC Neurosci. 2014. PMID: 24946931 Free PMC article. Review.

9

The functional significance of common polymorphisms in zinc finger transcription factors.

Lockwood SH, Guan A, Yu AS, Zhang C, Zykovich A, Korf I, Rannala B, Segal DJ. Lockwood SH, et al. Among authors: segal dj. G3 (Bethesda). 2014 Jun 26;4(9):1647-55. doi: 10.1534/g3.114.012195. G3 (Bethesda). 2014. PMID: 24970883 Free PMC article.

10

Miz-1 activates gene expression via a novel consensus DNA binding motif.

Barrilleaux BL, Burow D, Lockwood SH, Yu A, Segal DJ, Knoepfler PS. Barrilleaux BL, et al. Among authors: segal dj. PLoS One. 2014 Jul 1;9(7):e101151. doi: 10.1371/journal.pone.0101151. eCollection 2014. PLoS One. 2014. PMID: 24983942 Free PMC article.

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