Siems K - Search Results

1

Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria.

Weidner C, Rousseau M, Micikas RJ, Fischer C, Plauth A, Wowro SJ, Siems K, Hetterling G, Kliem M, Schroeder FC, Sauer S. Weidner C, et al. Among authors: siems k. J Nat Prod. 2016 Jan 22;79(1):2-12. doi: 10.1021/acs.jnatprod.5b00072. Epub 2016 Jan 5. J Nat Prod. 2016. PMID: 26731300

2

Amorfrutins are potent antidiabetic dietary natural products.

Weidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AF, Schroeder FC, Büssow K, Sauer S. Weidner C, et al. Among authors: siems k. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7257-62. doi: 10.1073/pnas.1116971109. Epub 2012 Apr 16. Proc Natl Acad Sci U S A. 2012. PMID: 22509006 Free PMC article.

3

Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties.

Weidner C, Wowro SJ, Freiwald A, Kawamoto K, Witzke A, Kliem M, Siems K, Müller-Kuhrt L, Schroeder FC, Sauer S. Weidner C, et al. Among authors: siems k. Diabetologia. 2013 Aug;56(8):1802-12. doi: 10.1007/s00125-013-2920-2. Epub 2013 May 18. Diabetologia. 2013. PMID: 23680913

4

Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.

El Amrani M, Lai D, Debbab A, Aly AH, Siems K, Seidel C, Schnekenburger M, Gaigneaux A, Diederich M, Feger D, Lin W, Proksch P. El Amrani M, et al. Among authors: siems k. J Nat Prod. 2014 Jan 24;77(1):49-56. doi: 10.1021/np4005745. Epub 2013 Dec 16. J Nat Prod. 2014. PMID: 24328302

5

New trichothecenes isolated from Holarrhena floribunda.

Loukaci A, Kayser O, Bindseil K, Siems K, Frevert J, Abreu PM. Loukaci A, et al. Among authors: siems k. J Nat Prod. 2000 Jan;63(1):52-6. doi: 10.1021/np990332l. J Nat Prod. 2000. PMID: 10650079

6

Merrekentrones A-D, ipomeamarone-like furanosesquiterpenes from Merremia kentrocaulos.

Jenett-Siems K, Siems K, Witte L, Eich E. Jenett-Siems K, et al. Among authors: siems k. J Nat Prod. 2001 Nov;64(11):1471-3. doi: 10.1021/np010233j. J Nat Prod. 2001. PMID: 11720538

7

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent.

Sourbier C, Scroggins BT, Mannes PZ, Liao PJ, Siems K, Wolf D, Beutler JA, Linehan WM, Neckers L. Sourbier C, et al. Among authors: siems k. Oncotarget. 2015 Oct 6;6(30):29963-74. doi: 10.18632/oncotarget.4676. Oncotarget. 2015. PMID: 26298773 Free PMC article.

8

Phytochemicals Rosmarinic Acid, Ampelopsin, and Amorfrutin-A Can Modulate Age-Related Phenotype of Serially Passaged Human Skin Fibroblasts in vitro.

Sodagam L, Lewinska A, Kwasniewicz E, Kokhanovska S, Wnuk M, Siems K, Rattan SIS. Sodagam L, et al. Among authors: siems k. Front Genet. 2019 Feb 21;10:81. doi: 10.3389/fgene.2019.00081. eCollection 2019. Front Genet. 2019. PMID: 30847003 Free PMC article.

9

Triterpene glycosides from the leaves of Pittosporum angustifolium.

Bäcker C, Jenett-Siems K, Siems K, Wurster M, Bodtke A, Chamseddin C, Crüsemann M, Lindequist U. Bäcker C, et al. Among authors: siems k. Planta Med. 2013 Oct;79(15):1461-9. doi: 10.1055/s-0033-1350806. Epub 2013 Sep 17. Planta Med. 2013. PMID: 24046217

10

Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.

Rubaiy HN, Ludlow MJ, Siems K, Norman K, Foster R, Wolf D, Beutler JA, Beech DJ. Rubaiy HN, et al. Among authors: siems k. Br J Pharmacol. 2018 Aug;175(16):3361-3368. doi: 10.1111/bph.14379. Epub 2018 Jun 28. Br J Pharmacol. 2018. PMID: 29859013 Free PMC article.

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