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Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.
Metzger E, Willmann D, McMillan J, Forne I, Metzger P, Gerhardt S, Petroll K, von Maessenhausen A, Urban S, Schott AK, Espejo A, Eberlin A, Wohlwend D, Schüle KM, Schleicher M, Perner S, Bedford MT, Jung M, Dengjel J, Flaig R, Imhof A, Einsle O, Schüle R. Metzger E, et al. Among authors: jung m. Nat Struct Mol Biol. 2016 Feb;23(2):132-9. doi: 10.1038/nsmb.3153. Epub 2016 Jan 11. Nat Struct Mol Biol. 2016. PMID: 26751641
A novel arginine methyltransferase inhibitor with cellular activity.
Spannhoff A, Machmur R, Heinke R, Trojer P, Bauer I, Brosch G, Schüle R, Hanefeld W, Sippl W, Jung M. Spannhoff A, et al. Among authors: jung m. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4150-3. doi: 10.1016/j.bmcl.2007.05.088. Epub 2007 Jun 3. Bioorg Med Chem Lett. 2007. PMID: 17570663
Chemical probes: sharpen your epigenetic tools.
Hauser AT, Jung M. Hauser AT, et al. Among authors: jung m. Nat Chem Biol. 2011 Jul 18;7(8):499-500. doi: 10.1038/nchembio.615. Nat Chem Biol. 2011. PMID: 21769094 No abstract available.
The role of histone demethylases in cancer therapy.
Hoffmann I, Roatsch M, Schmitt ML, Carlino L, Pippel M, Sippl W, Jung M. Hoffmann I, et al. Among authors: jung m. Mol Oncol. 2012 Dec;6(6):683-703. doi: 10.1016/j.molonc.2012.07.004. Epub 2012 Aug 7. Mol Oncol. 2012. PMID: 22902149 Free PMC article. Review.
Current trends in epigenetic drug discovery.
Stolfa DA, Einsle O, Sippl W, Jung M. Stolfa DA, et al. Among authors: jung m. Future Med Chem. 2012 Oct;4(16):2029-37. doi: 10.4155/fmc.12.144. Future Med Chem. 2012. PMID: 23157236
5,596 results