Hurley KA - Search Results

1

Targeting the Bacterial Division Protein FtsZ.

Hurley KA, Santos TM, Nepomuceno GM, Huynh V, Shaw JT, Weibel DB. Hurley KA, et al. J Med Chem. 2016 Aug 11;59(15):6975-98. doi: 10.1021/acs.jmedchem.5b01098. Epub 2016 Mar 10. J Med Chem. 2016. PMID: 26756351 Review.

2

N-Benzyl-3-sulfonamidopyrrolidines are a New Class of Bacterial DNA Gyrase Inhibitors.

Foss MH, Hurley KA, Sorto N, Lackner LL, Thornton KM, Shaw JT, Weibel DB. Foss MH, et al. Among authors: hurley ka. ACS Med Chem Lett. 2011 Apr 14;2(4):289-292. doi: 10.1021/ml1002822. ACS Med Chem Lett. 2011. PMID: 21552338 Free PMC article.

3

5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics.

Faulkner KC, Hurley KA, Weibel DB. Faulkner KC, et al. Among authors: hurley ka. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5539-5544. doi: 10.1016/j.bmcl.2016.10.004. Epub 2016 Oct 5. Bioorg Med Chem Lett. 2016. PMID: 27765507 Free PMC article.

4

Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology.

Rajendram M, Hurley KA, Foss MH, Thornton KM, Moore JT, Shaw JT, Weibel DB. Rajendram M, et al. Among authors: hurley ka. ACS Chem Biol. 2014 Jun 20;9(6):1312-9. doi: 10.1021/cb500154m. Epub 2014 Apr 22. ACS Chem Biol. 2014. PMID: 24712739 Free PMC article.

5

Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria.

Hurley KA, Heinrich VA, Hershfield JR, Demons ST, Weibel DB. Hurley KA, et al. ACS Med Chem Lett. 2015 Mar 1;6(4):466-71. doi: 10.1021/acsmedchemlett.5b00024. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941556 Free PMC article.

6

Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase.

Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, Blahnik BJ, Faulkner KC, Foss MH, Heinrich VA, Lammers MG, Moore LC, Reynolds GD, Shearn-Nance GP, Stearns BA, Yao ZW, Shaw JT, Weibel DB. Hurley KA, et al. Medchemcomm. 2017;8(5):942-951. doi: 10.1039/C7MD00012J. Epub 2017 Feb 27. Medchemcomm. 2017. PMID: 30034678 Free PMC article.

7

Synthesis of a γ-lactam library via formal cycloaddition of imines and substituted succinic anhydrides.

Tan DQ, Atherton AL, Smith AJ, Soldi C, Hurley KA, Fettinger JC, Shaw JT. Tan DQ, et al. Among authors: hurley ka. ACS Comb Sci. 2012 Mar 12;14(3):218-23. doi: 10.1021/co2001873. Epub 2012 Feb 10. ACS Comb Sci. 2012. PMID: 22225535 Free PMC article.

8

Pathogenic and Commensal Gut Bacteria Harboring Glycerol/Diol Dehydratase Metabolize Glycerol and Produce DNA-Reactive Acrolein.

Ramirez Garcia A, Hurley K, Marastoni G, Diard M, Hofer S, Greppi A, Hardt WD, Lacroix C, Sturla SJ, Schwab C. Ramirez Garcia A, et al. Chem Res Toxicol. 2022 Oct 17;35(10):1840-1850. doi: 10.1021/acs.chemrestox.2c00137. Epub 2022 Sep 18. Chem Res Toxicol. 2022. PMID: 36116084 Free PMC article.

9

Impact of manipulation of glycerol/diol dehydratase activity on intestinal microbiota ecology and metabolism.

Ramirez Garcia A, Zhang J, Greppi A, Constancias F, Wortmann E, Wandres M, Hurley K, Pascual-García A, Ruscheweyh HJ, Sturla SJ, Lacroix C, Schwab C. Ramirez Garcia A, et al. Environ Microbiol. 2021 Mar;23(3):1765-1779. doi: 10.1111/1462-2920.15431. Epub 2021 Mar 15. Environ Microbiol. 2021. PMID: 33587772

10

Enzymatic Acrolein Production System and Its Impact on Human Cells.

Hurley KA, Folz J, Zgraggen J, Cruz TN, Diedrich S, Sturla SJ. Hurley KA, et al. Chem Res Toxicol. 2024 Aug 19;37(8):1374-1381. doi: 10.1021/acs.chemrestox.4c00119. Epub 2024 Jul 9. Chem Res Toxicol. 2024. PMID: 39155646 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

17 results

Search Page

Filters