Huang M - Search Results

1

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Hu J, Wang X, Chen L, Huang M, Tang W, Zuo J, Liu YC, Shi Z, Liu R, Shen J, Xiong B. Hu J, et al. Among authors: huang m. Bioorg Med Chem Lett. 2016 Feb 1;26(3):721-725. doi: 10.1016/j.bmcl.2016.01.006. Epub 2016 Jan 7. Bioorg Med Chem Lett. 2016. PMID: 26776360

2

Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2).

Li L, Liu F, Jin N, Tang S, Chen Z, Yang X, Ding J, Geng M, Jiang L, Huang M, Cao J. Li L, et al. Among authors: huang m. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2600-4. doi: 10.1016/j.bmcl.2016.04.029. Epub 2016 Apr 12. Bioorg Med Chem Lett. 2016. PMID: 27106711

3

Metalloform-selective inhibition: synthesis and structure-activity analysis of Mn(II)-form-selective inhibitors of Escherichia coli methionine aminopeptidase.

Huang QQ, Huang M, Nan FJ, Ye QZ. Huang QQ, et al. Among authors: huang m. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5386-91. doi: 10.1016/j.bmcl.2005.09.019. Epub 2005 Oct 10. Bioorg Med Chem Lett. 2005. PMID: 16219464

4

Development of the First Generation of Disulfide-Based Subtype-Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors.

Liu Y, Xie Z, Zhao D, Zhu J, Mao F, Tang S, Xu H, Luo C, Geng M, Huang M, Li J. Liu Y, et al. Among authors: huang m. J Med Chem. 2017 Mar 23;60(6):2227-2244. doi: 10.1021/acs.jmedchem.6b01245. Epub 2017 Mar 6. J Med Chem. 2017. PMID: 28230989

5

Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition.

Sun D, Liu H, Dai X, Zheng X, Yan J, Wei R, Fu X, Huang M, Shen A, Huang X, Ding J, Geng M. Sun D, et al. Among authors: huang m, huang x. Cancer Lett. 2017 Oct 10;406:105-115. doi: 10.1016/j.canlet.2017.06.029. Epub 2017 Jul 5. Cancer Lett. 2017. PMID: 28687354

6

Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase.

Dai X, Yan J, Fu X, Pan Q, Sun D, Xu Y, Wang J, Nie L, Tong L, Shen A, Zheng M, Huang M, Tan M, Liu H, Huang X, Ding J, Geng M. Dai X, et al. Among authors: huang m, huang x. Clin Cancer Res. 2017 Oct 15;23(20):6267-6278. doi: 10.1158/1078-0432.CCR-17-0242. Epub 2017 Jul 14. Clin Cancer Res. 2017. PMID: 28710312

7

c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors.

Liu H, Ai J, Shen A, Chen Y, Wang X, Peng X, Chen H, Shen Y, Huang M, Ding J, Geng M. Liu H, et al. Among authors: huang m. Clin Cancer Res. 2017 Feb 15;23(4):974-984. doi: 10.1158/1078-0432.CCR-15-2448. Epub 2016 Jul 11. Clin Cancer Res. 2017. PMID: 27401245

8

Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.

Wang WL, Chai SC, Huang M, He HZ, Hurley TD, Ye QZ. Wang WL, et al. Among authors: huang m. J Med Chem. 2008 Oct 9;51(19):6110-20. doi: 10.1021/jm8005788. Epub 2008 Sep 12. J Med Chem. 2008. PMID: 18785729 Free PMC article.

9

One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates.

Tang F, Yang Y, Tang Y, Tang S, Yang L, Sun B, Jiang B, Dong J, Liu H, Huang M, Geng MY, Huang W. Tang F, et al. Among authors: huang m, huang w. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518. doi: 10.1039/c6ob01751g. Org Biomol Chem. 2016. PMID: 27714198

10

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

Zeng H, Qu J, Jin N, Xu J, Lin C, Chen Y, Yang X, He X, Tang S, Lan X, Yang X, Chen Z, Huang M, Ding J, Geng M. Zeng H, et al. Among authors: huang m. Cancer Cell. 2016 Sep 12;30(3):459-473. doi: 10.1016/j.ccell.2016.08.001. Cancer Cell. 2016. PMID: 27622335 Free article.

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