Xiong B - Search Results

1

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Hu J, Wang X, Chen L, Huang M, Tang W, Zuo J, Liu YC, Shi Z, Liu R, Shen J, Xiong B. Hu J, et al. Among authors: xiong b. Bioorg Med Chem Lett. 2016 Feb 1;26(3):721-725. doi: 10.1016/j.bmcl.2016.01.006. Epub 2016 Jan 7. Bioorg Med Chem Lett. 2016. PMID: 26776360

2

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Liu H, Huang X, Shen J, Luo X, Li M, Xiong B, Chen G, Shen J, Yang Y, Jiang H, Chen K. Liu H, et al. Among authors: xiong b. J Med Chem. 2002 Oct 24;45(22):4816-27. doi: 10.1021/jm020089e. J Med Chem. 2002. PMID: 12383007

3

Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to beta-secretase.

Hu B, Xiong B, Qiu BY, Li X, Yu HP, Xiao K, Wang X, Li J, Shen JK. Hu B, et al. Among authors: xiong b. Acta Pharmacol Sin. 2006 Dec;27(12):1586-93. doi: 10.1111/j.1745-7254.2006.00432.x. Acta Pharmacol Sin. 2006. PMID: 17112413

4

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.

Zhang L, Qiu B, Xiong B, Li X, Li J, Wang X, Li J, Shen J. Zhang L, et al. Among authors: xiong b. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2118-22. doi: 10.1016/j.bmcl.2007.01.094. Epub 2007 Feb 2. Bioorg Med Chem Lett. 2007. PMID: 17303416

5

Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.

Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J, Shen J. Ling Q, et al. Among authors: xiong b. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409. doi: 10.1016/j.bmc.2008.06.014. Epub 2008 Jun 13. Bioorg Med Chem. 2008. PMID: 18579388

6

DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks.

Xiong B, Liu K, Wu J, Burk DL, Jiang H, Shen J. Xiong B, et al. Bioinformatics. 2008 Sep 15;24(18):2117-8. doi: 10.1093/bioinformatics/btn389. Epub 2008 Jul 25. Bioinformatics. 2008. PMID: 18658180

7

ScafBank: a public comprehensive Scaffold database to support molecular hopping.

Yan BB, Xue MZ, Xiong B, Liu K, Hu DY, Shen JK. Yan BB, et al. Among authors: xiong b. Acta Pharmacol Sin. 2009 Feb;30(2):251-8. doi: 10.1038/aps.2008.22. Epub 2009 Jan 19. Acta Pharmacol Sin. 2009. PMID: 19151741 Free PMC article.

8

Discovery of potent beta-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids.

Zhu YP, Xiao K, Yu HP, Ma LP, Xiong B, Zhang HY, Wang X, Li JY, Li J, Shen JK. Zhu YP, et al. Among authors: xiong b. Acta Pharmacol Sin. 2009 Feb;30(2):259-69. doi: 10.1038/aps.2008.26. Epub 2009 Jan 26. Acta Pharmacol Sin. 2009. PMID: 19169270 Free PMC article.

9

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.

Zhang Z, Meng T, He J, Li M, Tong LJ, Xiong B, Lin L, Shen J, Miao ZH, Ding J. Zhang Z, et al. Among authors: xiong b. Invest New Drugs. 2010 Dec;28(6):715-28. doi: 10.1007/s10637-009-9303-z. Epub 2009 Aug 25. Invest New Drugs. 2010. PMID: 19705064

10

Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.

Meng T, Wang J, Peng H, Fang G, Li M, Xiong B, Xie X, Zhang Y, Wang X, Shen J. Meng T, et al. Among authors: xiong b. Eur J Med Chem. 2010 Mar;45(3):1133-9. doi: 10.1016/j.ejmech.2009.12.018. Epub 2009 Dec 16. Eur J Med Chem. 2010. PMID: 20047779

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