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Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2.
El Karoui K, Viau A, Dellis O, Bagattin A, Nguyen C, Baron W, Burtin M, Broueilh M, Heidet L, Mollet G, Druilhe A, Antignac C, Knebelmann B, Friedlander G, Bienaimé F, Gallazzini M, Terzi F. El Karoui K, et al. Among authors: friedlander g. Nat Commun. 2016 Jan 20;7:10330. doi: 10.1038/ncomms10330. Nat Commun. 2016. PMID: 26787103 Free PMC article.
Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.
Viau A, El Karoui K, Laouari D, Burtin M, Nguyen C, Mori K, Pillebout E, Berger T, Mak TW, Knebelmann B, Friedlander G, Barasch J, Terzi F. Viau A, et al. Among authors: friedlander g. J Clin Invest. 2010 Nov;120(11):4065-76. doi: 10.1172/JCI42004. J Clin Invest. 2010. PMID: 20921623 Free PMC article.
TGF-alpha mediates genetic susceptibility to chronic kidney disease.
Laouari D, Burtin M, Phelep A, Martino C, Pillebout E, Montagutelli X, Friedlander G, Terzi F. Laouari D, et al. Among authors: friedlander g. J Am Soc Nephrol. 2011 Feb;22(2):327-35. doi: 10.1681/ASN.2010040356. Epub 2010 Dec 23. J Am Soc Nephrol. 2011. PMID: 21183591 Free PMC article.
A transcriptional network underlies susceptibility to kidney disease progression.
Laouari D, Burtin M, Phelep A, Bienaime F, Noel LH, Lee DC, Legendre C, Friedlander G, Pontoglio M, Terzi F. Laouari D, et al. Among authors: friedlander g. EMBO Mol Med. 2012 Aug;4(8):825-39. doi: 10.1002/emmm.201101127. Epub 2012 Jun 18. EMBO Mol Med. 2012. PMID: 22711280 Free PMC article.
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Canaud G, Bienaimé F, Viau A, Treins C, Baron W, Nguyen C, Burtin M, Berissi S, Giannakakis K, Muda AO, Zschiedrich S, Huber TB, Friedlander G, Legendre C, Pontoglio M, Pende M, Terzi F. Canaud G, et al. Among authors: friedlander g. Nat Med. 2013 Oct;19(10):1288-96. doi: 10.1038/nm.3313. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056770
Stat3 Controls Tubulointerstitial Communication during CKD.
Bienaimé F, Muorah M, Yammine L, Burtin M, Nguyen C, Baron W, Garbay S, Viau A, Broueilh M, Blanc T, Peters D, Poli V, Anglicheau D, Friedlander G, Pontoglio M, Gallazzini M, Terzi F. Bienaimé F, et al. Among authors: friedlander g. J Am Soc Nephrol. 2016 Dec;27(12):3690-3705. doi: 10.1681/ASN.2015091014. Epub 2016 May 6. J Am Soc Nephrol. 2016. PMID: 27153926 Free PMC article.
MITF - A controls branching morphogenesis and nephron endowment.
Phelep A, Laouari D, Bharti K, Burtin M, Tammaccaro S, Garbay S, Nguyen C, Vasseur F, Blanc T, Berissi S, Langa-Vives F, Fischer E, Druilhe A, Arnheiter H, Friedlander G, Pontoglio M, Terzi F. Phelep A, et al. Among authors: friedlander g. PLoS Genet. 2017 Dec 14;13(12):e1007093. doi: 10.1371/journal.pgen.1007093. eCollection 2017 Dec. PLoS Genet. 2017. PMID: 29240767 Free PMC article.
295 results