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Page 1
Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach.
Fontaine SN, Ingram A, Cloyd RA, Meier SE, Miller E, Lyons D, Nation GK, Mechas E, Weiss B, Lanzillotta C, Di Domenico F, Schmitt F, Powell DK, Vandsburger M, Abisambra JF. Fontaine SN, et al. Neurobiol Aging. 2017 Aug;56:78-86. doi: 10.1016/j.neurobiolaging.2017.04.007. Epub 2017 Apr 18. Neurobiol Aging. 2017. PMID: 28500878 Free PMC article.
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy.
Koren SA, Hamm MJ, Cloyd R, Fontaine SN, Chishti E, Lanzillotta C, Rodriguez-Rivera J, Ingram A, Bell M, Galvis-Escobar SM, Zulia N, Di Domenico F, Duong D, Seyfried NT, Powell D, Vandsburger M, Frolinger T, Hartz AMS, Koren J 3rd, Axten JM, Laping NJ, Abisambra JF. Koren SA, et al. Among authors: fontaine sn. Int J Mol Sci. 2021 Jan 26;22(3):1186. doi: 10.3390/ijms22031186. Int J Mol Sci. 2021. PMID: 33530349 Free PMC article.
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Sandusky-Beltran LA, Kovalenko A, Placides DS, Ratnasamy K, Ma C, Hunt JB Jr, Liang H, Calahatian JIT, Michalski C, Fahnestock M, Blair LJ, Darling AL, Baker JD, Fontaine SN, Dickey CA, Gamsby JJ, Nash KR, Abner E, Selenica MB, Lee DC. Sandusky-Beltran LA, et al. Among authors: fontaine sn. J Clin Invest. 2021 Feb 15;131(4):e126299. doi: 10.1172/JCI126299. J Clin Invest. 2021. PMID: 33586680 Free PMC article.
Cellular factors modulating the mechanism of tau protein aggregation.
Fontaine SN, Sabbagh JJ, Baker J, Martinez-Licha CR, Darling A, Dickey CA. Fontaine SN, et al. Cell Mol Life Sci. 2015 May;72(10):1863-79. doi: 10.1007/s00018-015-1839-9. Epub 2015 Feb 11. Cell Mol Life Sci. 2015. PMID: 25666877 Free PMC article. Review.
Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, Selenica MB, Nash KR, Gordon MN, Morgan D, Lee DC. Sandusky-Beltran LA, et al. Among authors: fontaine sn. Alzheimers Res Ther. 2019 Jun 29;11(1):58. doi: 10.1186/s13195-019-0507-y. Alzheimers Res Ther. 2019. PMID: 31253191 Free PMC article.
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC 3rd, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, Binder EB, Kayed R, Golde TE, Berchtold N, Dickey CA. Blair LJ, et al. Among authors: fontaine sn. J Clin Invest. 2013 Oct;123(10):4158-69. doi: 10.1172/JCI69003. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999428 Free PMC article.
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Martin MD, et al. Among authors: fontaine sn. ACS Chem Biol. 2015 Apr 17;10(4):1099-109. doi: 10.1021/cb501013w. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25588114 Free PMC article.
21 results