Guo Q - Search Results

1

Design and synthesis of novel 4'-demethyl-4-deoxypodophyllotoxin derivatives as potential anticancer agents.

Zhu X, Fu J, Tang Y, Gao Y, Zhang S, Guo Q. Zhu X, et al. Among authors: guo q. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1360-4. doi: 10.1016/j.bmcl.2015.06.089. Epub 2015 Jul 4. Bioorg Med Chem Lett. 2016. PMID: 26804229

2

Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase.

Cao X, You QD, Li ZY, Guo QL, Shang J, Yan M, Chern JW, Chen ML. Cao X, et al. Bioorg Med Chem. 2008 Jun 1;16(11):5890-8. doi: 10.1016/j.bmc.2008.04.065. Epub 2008 Apr 29. Bioorg Med Chem. 2008. PMID: 18485715

3

The design, synthesis and biological evaluation of 7-alkoxy-4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS.

Cao X, You QD, Li ZY, Liu XR, Xu D, Guo QL, Shang J, Chern JW, Chen ML. Cao X, et al. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6206-9. doi: 10.1016/j.bmcl.2008.10.006. Epub 2008 Oct 5. Bioorg Med Chem Lett. 2008. PMID: 18930653

4

Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid.

Wang J, Zhao L, Hu Y, Guo Q, Zhang L, Wang X, Li N, You Q. Wang J, et al. Among authors: guo q. Eur J Med Chem. 2009 Jun;44(6):2611-20. doi: 10.1016/j.ejmech.2008.09.034. Epub 2008 Oct 7. Eur J Med Chem. 2009. PMID: 18996626

5

Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors.

Li Z, Zhai F, Zhao L, Guo Q, You Q. Li Z, et al. Among authors: guo q. Bioorg Med Chem Lett. 2009 Jan 15;19(2):406-9. doi: 10.1016/j.bmcl.2008.11.061. Epub 2008 Nov 21. Bioorg Med Chem Lett. 2009. PMID: 19058964

6

Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53.

Rong JJ, Hu R, Qi Q, Gu HY, Zhao Q, Wang J, Mu R, You QD, Guo QL. Rong JJ, et al. Among authors: guo ql. Cancer Lett. 2009 Oct 18;284(1):102-12. doi: 10.1016/j.canlet.2009.04.011. Epub 2009 May 9. Cancer Lett. 2009. PMID: 19428175

7

[The design, synthesis and anticancer activity of 4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS].

Cao X, You QD, Li ZY, Guo QL, Yang Y, Shang J, Yan M, Chen JW, Chen ML. Cao X, et al. Yao Xue Xue Bao. 2009 Mar;44(3):288-95. Yao Xue Xue Bao. 2009. PMID: 19449526 Chinese.

8

Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification.

You QD, Li ZY, Huang CH, Yang Q, Wang XJ, Guo QL, Chen XG, He XG, Li TK, Chern JW. You QD, et al. Among authors: guo ql. J Med Chem. 2009 Sep 24;52(18):5649-61. doi: 10.1021/jm900469e. J Med Chem. 2009. PMID: 19715319

9

An oxidative analogue of gambogic acid-induced apoptosis of human hepatocellular carcinoma cell line HepG2 is involved in its anticancer activity in vitro.

Mu R, Lu N, Wang J, Yin Y, Ding Y, Zhang X, Gui H, Sun Q, Duan H, Zhang L, Zhang Y, Ke X, Guo Q. Mu R, et al. Among authors: guo q. Eur J Cancer Prev. 2010 Jan;19(1):61-7. doi: 10.1097/CEJ.0b013e328333fb22. Eur J Cancer Prev. 2010. PMID: 19934761

10

Synthesis and anti-human hepatocellular carcinoma activity of new nitric oxide-releasing glycosyl derivatives of oleanolic acid.

Huang Z, Zhang Y, Zhao L, Jing Y, Lai Y, Zhang L, Guo Q, Yuan S, Zhang J, Chen L, Peng S, Tian J. Huang Z, et al. Among authors: guo q. Org Biomol Chem. 2010 Feb 7;8(3):632-9. doi: 10.1039/b918846k. Epub 2009 Dec 8. Org Biomol Chem. 2010. PMID: 20090981

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