Kaarsholm NC - Search Results

1

Spectroscopic signatures of the T to R conformational transition in the insulin hexamer.

Roy M, Brader ML, Lee RW, Kaarsholm NC, Hansen JF, Dunn MF. Roy M, et al. Among authors: kaarsholm nc. J Biol Chem. 1989 Nov 15;264(32):19081-5. J Biol Chem. 1989. PMID: 2681208 Free article.

2

Studies of the association and conformational properties of metal-free insulin in alkaline sodium chloride solutions by one- and two-dimensional 1H NMR.

Kadima W, Roy M, Lee RW, Kaarsholm NC, Dunn MF. Kadima W, et al. Among authors: kaarsholm nc. J Biol Chem. 1992 May 5;267(13):8963-70. J Biol Chem. 1992. PMID: 1577733 Free article.

3

Characterization of the R-state insulin hexamer and its derivatives. The hexamer is stabilized by heterotropic ligand binding interactions.

Brader ML, Kaarsholm NC, Lee RW, Dunn MF. Brader ML, et al. Among authors: kaarsholm nc. Biochemistry. 1991 Jul 9;30(27):6636-45. doi: 10.1021/bi00241a002. Biochemistry. 1991. PMID: 2065051

4

The R-state proinsulin and insulin hexamers mimic the carbonic anhydrase active site.

Brader ML, Kaarsholm NC, Dunn MF. Brader ML, et al. Among authors: kaarsholm nc. J Biol Chem. 1990 Sep 15;265(26):15666-70. J Biol Chem. 1990. PMID: 2118529 Free article.

5

Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin.

Roy M, Lee RW, Kaarsholm NC, Thøgersen H, Brange J, Dunn MF. Roy M, et al. Among authors: kaarsholm nc. Biochim Biophys Acta. 1990 Jun 12;1053(1):63-73. doi: 10.1016/0167-4889(90)90027-b. Biochim Biophys Acta. 1990. PMID: 2194578

6

Structural asymmetry and half-site reactivity in the T to R allosteric transition of the insulin hexamer.

Brzović PS, Choi WE, Borchardt D, Kaarsholm NC, Dunn MF. Brzović PS, et al. Among authors: kaarsholm nc. Biochemistry. 1994 Nov 8;33(44):13057-69. doi: 10.1021/bi00248a015. Biochemistry. 1994. PMID: 7947711

7

The allosteric transition of the insulin hexamer is modulated by homotropic and heterotropic interactions.

Choi WE, Brader ML, Aguilar V, Kaarsholm NC, Dunn MF. Choi WE, et al. Among authors: kaarsholm nc. Biochemistry. 1993 Nov 2;32(43):11638-45. doi: 10.1021/bi00094a021. Biochemistry. 1993. PMID: 8218231

8

Spectroscopic evidence for preexisting T- and R-state insulin hexamer conformations.

Choi WE, Borchardt D, Kaarsholm NC, Brzovic PS, Dunn MF. Choi WE, et al. Among authors: kaarsholm nc. Proteins. 1996 Dec;26(4):377-90. doi: 10.1002/(SICI)1097-0134(199612)26:4<377::AID-PROT2>3.0.CO;2-9. Proteins. 1996. PMID: 8990494

9

Ligand perturbation effects on a pseudotetrahedral Co(II)(His)3-ligand site. A magnetic circular dichroism study of the Co(II)-substituted insulin hexamer.

Brader ML, Kaarsholm NC, Harnung SE, Dunn MF. Brader ML, et al. Among authors: kaarsholm nc. J Biol Chem. 1997 Jan 10;272(2):1088-94. doi: 10.1074/jbc.272.2.1088. J Biol Chem. 1997. PMID: 8995407 Free article.

10

Mechanisms of stabilization of the insulin hexamer through allosteric ligand interactions.

Rahuel-Clermont S, French CA, Kaarsholm NC, Dunn MF, Chou CI. Rahuel-Clermont S, et al. Among authors: kaarsholm nc. Biochemistry. 1997 May 13;36(19):5837-45. doi: 10.1021/bi963038q. Biochemistry. 1997. PMID: 9153424

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