Brady OA - Search Results

1

TFEB and TFE3 are novel components of the integrated stress response.

Martina JA, Diab HI, Brady OA, Puertollano R. Martina JA, et al. Among authors: brady oa. EMBO J. 2016 Mar 1;35(5):479-95. doi: 10.15252/embj.201593428. Epub 2016 Jan 25. EMBO J. 2016. PMID: 26813791 Free PMC article.

2

TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages.

Pastore N, Brady OA, Diab HI, Martina JA, Sun L, Huynh T, Lim JA, Zare H, Raben N, Ballabio A, Puertollano R. Pastore N, et al. Among authors: brady oa. Autophagy. 2016 Aug 2;12(8):1240-58. doi: 10.1080/15548627.2016.1179405. Epub 2016 May 12. Autophagy. 2016. PMID: 27171064 Free PMC article.

3

Rags to riches: Amino acid sensing by the Rag GTPases in health and disease.

Brady OA, Diab HI, Puertollano R. Brady OA, et al. Small GTPases. 2016 Oct;7(4):197-206. doi: 10.1080/21541248.2016.1218990. Epub 2016 Aug 31. Small GTPases. 2016. PMID: 27580159 Free PMC article. Review.

4

Emerging roles for TFEB in the immune response and inflammation.

Brady OA, Martina JA, Puertollano R. Brady OA, et al. Autophagy. 2018;14(2):181-189. doi: 10.1080/15548627.2017.1313943. Epub 2017 Jul 24. Autophagy. 2018. PMID: 28738171 Free PMC article. Review.

5

The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage.

Brady OA, Jeong E, Martina JA, Pirooznia M, Tunc I, Puertollano R. Brady OA, et al. Elife. 2018 Dec 6;7:e40856. doi: 10.7554/eLife.40856. Elife. 2018. PMID: 30520728 Free PMC article.

6

Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1.

Brady OA, Meng P, Zheng Y, Mao Y, Hu F. Brady OA, et al. J Neurochem. 2011 Jan;116(2):248-59. doi: 10.1111/j.1471-4159.2010.07098.x. Epub 2010 Dec 2. J Neurochem. 2011. PMID: 21062285 Free article.

7

C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking.

Zheng Y, Brady OA, Meng PS, Mao Y, Hu F. Zheng Y, et al. Among authors: brady oa. PLoS One. 2011;6(6):e21023. doi: 10.1371/journal.pone.0021023. Epub 2011 Jun 15. PLoS One. 2011. PMID: 21698296 Free PMC article.

8

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.

Brady OA, Zheng Y, Murphy K, Huang M, Hu F. Brady OA, et al. Hum Mol Genet. 2013 Feb 15;22(4):685-95. doi: 10.1093/hmg/dds475. Epub 2012 Nov 6. Hum Mol Genet. 2013. PMID: 23136129 Free PMC article.

9

Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency.

Zhou X, Sun L, Brady OA, Murphy KA, Hu F. Zhou X, et al. Among authors: brady oa. Acta Neuropathol Commun. 2017 Jan 26;5(1):9. doi: 10.1186/s40478-017-0412-1. Acta Neuropathol Commun. 2017. PMID: 28126008 Free PMC article.

10

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM. Hu F, et al. Among authors: brady oa. Neuron. 2010 Nov 18;68(4):654-67. doi: 10.1016/j.neuron.2010.09.034. Neuron. 2010. PMID: 21092856 Free PMC article.

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