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Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans.
Kuhre RE, Gribble FM, Hartmann B, Reimann F, Windeløv JA, Rehfeld JF, Holst JJ. Kuhre RE, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 1;306(7):G622-30. doi: 10.1152/ajpgi.00372.2013. Epub 2014 Feb 13. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24525020 Free PMC article.
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production.
Wewer Albrechtsen NJ, Kuhre RE, Hornburg D, Jensen CZ, Hornum M, Dirksen C, Svane M, Gasbjerg LS, Jørgensen NB, Gabe MN, Balk-Møller E, Albrechtsen R, Winther-Sørensen M, Galsgaard KD, Meissner F, Jorsal T, Lund A, Vilsbøll T, Eliasen R, Bojsen-Møller KN, Idorn T, Deacon CF, Knop FK, Rosenkilde MM, Hartmann B, Feldt-Rasmussen B, Mann M, Madsbad S, Holst JJ. Wewer Albrechtsen NJ, et al. Among authors: kuhre re. Cell Rep. 2017 Nov 7;21(6):1452-1460. doi: 10.1016/j.celrep.2017.10.034. Cell Rep. 2017. PMID: 29117552 Free PMC article.
Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.
Kuhre RE, Wewer Albrechtsen NJ, Larsen O, Jepsen SL, Balk-Møller E, Andersen DB, Deacon CF, Schoonjans K, Reimann F, Gribble FM, Albrechtsen R, Hartmann B, Rosenkilde MM, Holst JJ. Kuhre RE, et al. Mol Metab. 2018 May;11:84-95. doi: 10.1016/j.molmet.2018.03.007. Epub 2018 Mar 17. Mol Metab. 2018. PMID: 29656109 Free PMC article.
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.
Kuhre RE, Modvig IM, Jepsen SL, Kizilkaya HS, Bæch-Laursen C, Smith CA, Reimann F, Gribble FM, Rosenkilde MM, Holst JJ. Kuhre RE, et al. Front Endocrinol (Lausanne). 2021 Aug 5;12:690387. doi: 10.3389/fendo.2021.690387. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34421821 Free PMC article.
58 results