Isaac L - Search Results

1

Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion.

Castiblanco-Valencia MM, Fraga TR, Pagotto AH, Serrano SM, Abreu PA, Barbosa AS, Isaac L. Castiblanco-Valencia MM, et al. Among authors: isaac l. Immunobiology. 2016 May;221(5):679-89. doi: 10.1016/j.imbio.2016.01.001. Epub 2016 Jan 7. Immunobiology. 2016. PMID: 26822552

2

Complement components, regulators and receptors are produced by human monocyte-derived dendritic cells.

Reis ES, Barbuto JA, Isaac L. Reis ES, et al. Among authors: isaac l. Immunobiology. 2007;212(3):151-7. doi: 10.1016/j.imbio.2006.11.010. Epub 2007 Jan 3. Immunobiology. 2007. PMID: 17412282

3

Immune evasion of leptospira species by acquisition of human complement regulator C4BP.

Barbosa AS, Abreu PA, Vasconcellos SA, Morais ZM, Gonçales AP, Silva AS, Daha MR, Isaac L. Barbosa AS, et al. Among authors: isaac l. Infect Immun. 2009 Mar;77(3):1137-43. doi: 10.1128/IAI.01310-08. Epub 2008 Dec 29. Infect Immun. 2009. PMID: 19114549 Free PMC article.

4

Skipping of exon 30 in C5 gene results in complete human C5 deficiency and demonstrates the importance of C5d and CUB domains for stability.

Aguilar-Ramirez P, Reis ES, Florido MP, Barbosa AS, Farah CS, Costa-Carvalho BT, Isaac L. Aguilar-Ramirez P, et al. Among authors: isaac l. Mol Immunol. 2009 Jun;46(10):2116-23. doi: 10.1016/j.molimm.2008.10.035. Epub 2009 Apr 16. Mol Immunol. 2009. PMID: 19375167

5

Functional characterization of LcpA, a surface-exposed protein of Leptospira spp. that binds the human complement regulator C4BP.

Barbosa AS, Monaris D, Silva LB, Morais ZM, Vasconcellos SA, Cianciarullo AM, Isaac L, Abreu PA. Barbosa AS, et al. Among authors: isaac l. Infect Immun. 2010 Jul;78(7):3207-16. doi: 10.1128/IAI.00279-10. Epub 2010 Apr 19. Infect Immun. 2010. PMID: 20404075 Free PMC article.

6

Leptospirosis: aspects of innate immunity, immunopathogenesis and immune evasion from the complement system.

Fraga TR, Barbosa AS, Isaac L. Fraga TR, et al. Among authors: isaac l. Scand J Immunol. 2011 May;73(5):408-19. doi: 10.1111/j.1365-3083.2010.02505.x. Scand J Immunol. 2011. PMID: 21204903 Free article. Review.

7

Leptospiral immunoglobulin-like proteins interact with human complement regulators factor H, FHL-1, FHR-1, and C4BP.

Castiblanco-Valencia MM, Fraga TR, Silva LB, Monaris D, Abreu PA, Strobel S, Józsi M, Isaac L, Barbosa AS. Castiblanco-Valencia MM, et al. Among authors: isaac l. J Infect Dis. 2012 Mar 15;205(6):995-1004. doi: 10.1093/infdis/jir875. Epub 2012 Jan 30. J Infect Dis. 2012. PMID: 22291192

8

Interaction of human complement factor H variants Tyr⁴⁰² and His⁴⁰² with Leptospira spp.

Silva AS, Valencia MM, Cianciarullo AM, Vasconcellos SA, Barbosa AS, Isaac L. Silva AS, et al. Among authors: isaac l. Front Immunol. 2011 Oct 5;2:44. doi: 10.3389/fimmu.2011.00044. eCollection 2011. Front Immunol. 2011. PMID: 22566834 Free PMC article.

9

Chemical chaperones curcumin and 4-phenylbutyric acid improve secretion of mutant factor H R127H by fibroblasts from a factor H-deficient patient.

Albuquerque JA, Lamers ML, Castiblanco-Valencia MM, Dos Santos M, Isaac L. Albuquerque JA, et al. Among authors: isaac l. J Immunol. 2012 Sep 15;189(6):3242-8. doi: 10.4049/jimmunol.1201418. Epub 2012 Aug 17. J Immunol. 2012. PMID: 22904312 Free article.

10

Immune evasion by pathogenic Leptospira strains: the secretion of proteases that directly cleave complement proteins.

Fraga TR, Courrol Ddos S, Castiblanco-Valencia MM, Hirata IY, Vasconcellos SA, Juliano L, Barbosa AS, Isaac L. Fraga TR, et al. Among authors: isaac l. J Infect Dis. 2014 Mar;209(6):876-86. doi: 10.1093/infdis/jit569. Epub 2013 Oct 26. J Infect Dis. 2014. PMID: 24163418

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