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The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups.
Hausmann R, Rettinger J, Gerevich Z, Meis S, Kassack MU, Illes P, Lambrecht G, Schmalzing G. Hausmann R, et al. Among authors: illes p. Mol Pharmacol. 2006 Jun;69(6):2058-67. doi: 10.1124/mol.106.022665. Epub 2006 Mar 21. Mol Pharmacol. 2006. PMID: 16551782
P2X3 receptor involvement in pain states.
Wirkner K, Sperlagh B, Illes P. Wirkner K, et al. Among authors: illes p. Mol Neurobiol. 2007 Oct;36(2):165-83. doi: 10.1007/s12035-007-0033-y. Epub 2007 Jul 17. Mol Neurobiol. 2007. PMID: 17952660 Review.
P2Y receptors and pain transmission.
Gerevich Z, Illes P. Gerevich Z, et al. Among authors: illes p. Purinergic Signal. 2004 Dec;1(1):3-10. doi: 10.1007/s11302-004-4740-9. Purinergic Signal. 2004. PMID: 18404394 Free PMC article.
Amino acid residues constituting the agonist binding site of the human P2X3 receptor.
Bodnar M, Wang H, Riedel T, Hintze S, Kato E, Fallah G, Gröger-Arndt H, Giniatullin R, Grohmann M, Hausmann R, Schmalzing G, Illes P, Rubini P. Bodnar M, et al. Among authors: illes p. J Biol Chem. 2011 Jan 28;286(4):2739-49. doi: 10.1074/jbc.M110.167437. Epub 2010 Nov 22. J Biol Chem. 2011. PMID: 21098022 Free PMC article.
377 results