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Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.
Trebicka J, Racz I, Siegmund SV, Cara E, Granzow M, Schierwagen R, Klein S, Wojtalla A, Hennenberg M, Huss S, Fischer HP, Heller J, Zimmer A, Sauerbruch T. Trebicka J, et al. Among authors: klein s. Liver Int. 2011 Jul;31(6):860-70. doi: 10.1111/j.1478-3231.2011.02496.x. Epub 2011 Mar 8. Liver Int. 2011. PMID: 21645218
The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes.
Wojtalla A, Herweck F, Granzow M, Klein S, Trebicka J, Huss S, Lerner R, Lutz B, Schildberg FA, Knolle PA, Sauerbruch T, Singer MV, Zimmer A, Siegmund SV. Wojtalla A, et al. Among authors: klein s. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G873-87. doi: 10.1152/ajpgi.00241.2011. Epub 2012 Feb 2. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22301114 Free article.
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats.
Klein S, Klösel J, Schierwagen R, Körner C, Granzow M, Huss S, Mazar IG, Weber S, van den Ven PF, Pieper-Fürst U, Fürst DO, Nattermann J, Lammert F, Sauerbruch T, Trebicka J. Klein S, et al. Lab Invest. 2012 Oct;92(10):1440-50. doi: 10.1038/labinvest.2012.106. Epub 2012 Aug 13. Lab Invest. 2012. PMID: 22890553 Free article.
3,804 results