Kuhns MS - Search Results

1

Functional evidence for TCR-intrinsic specificity for MHCII.

Parrish HL, Deshpande NR, Vasic J, Kuhns MS. Parrish HL, et al. Among authors: kuhns ms. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3000-5. doi: 10.1073/pnas.1518499113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831112 Free PMC article.

2

Evidence for a functional sidedness to the alphabetaTCR.

Kuhns MS, Girvin AT, Klein LO, Chen R, Jensen KD, Newell EW, Huppa JB, Lillemeier BF, Huse M, Chien YH, Garcia KC, Davis MM. Kuhns MS, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5094-9. doi: 10.1073/pnas.1000925107. Epub 2010 Mar 2. Proc Natl Acad Sci U S A. 2010. PMID: 20202921 Free PMC article.

3

Piecing together the family portrait of TCR-CD3 complexes.

Kuhns MS, Badgandi HB. Kuhns MS, et al. Immunol Rev. 2012 Nov;250(1):120-43. doi: 10.1111/imr.12000. Immunol Rev. 2012. PMID: 23046126 Review.

4

A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

Parrish HL, Glassman CR, Keenen MM, Deshpande NR, Bronnimann MP, Kuhns MS. Parrish HL, et al. Among authors: kuhns ms. PLoS One. 2015 Jul 6;10(7):e0132333. doi: 10.1371/journal.pone.0132333. eCollection 2015. PLoS One. 2015. PMID: 26147390 Free PMC article.

5

Self-recognition drives the preferential accumulation of promiscuous CD4(+) T-cells in aged mice.

Deshpande NR, Parrish HL, Kuhns MS. Deshpande NR, et al. Among authors: kuhns ms. Elife. 2015 Jul 14;4:e05949. doi: 10.7554/eLife.05949. Elife. 2015. PMID: 26173205 Free PMC article.

6

A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ.

Lee MS, Glassman CR, Deshpande NR, Badgandi HB, Parrish HL, Uttamapinant C, Stawski PS, Ting AY, Kuhns MS. Lee MS, et al. Among authors: kuhns ms. Immunity. 2015 Aug 18;43(2):227-39. doi: 10.1016/j.immuni.2015.06.018. Epub 2015 Jul 28. Immunity. 2015. PMID: 26231119 Free PMC article.

7

Correction: A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

Parrish HL, Glassman CR, Keenen MM, Deshpande NR, Bronnimann MP, Kuhns MS. Parrish HL, et al. Among authors: kuhns ms. PLoS One. 2016 Mar 1;11(3):e0150876. doi: 10.1371/journal.pone.0150876. eCollection 2016. PLoS One. 2016. PMID: 26930656 Free PMC article. No abstract available.

8

The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR-CD3-pMHC-CD4 Macrocomplex.

Glassman CR, Parrish HL, Deshpande NR, Kuhns MS. Glassman CR, et al. Among authors: kuhns ms. J Immunol. 2016 Jun 1;196(11):4713-22. doi: 10.4049/jimmunol.1502110. Epub 2016 May 2. J Immunol. 2016. PMID: 27183595 Free PMC article.

9

Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex.

Glassman CR, Parrish HL, Lee MS, Kuhns MS. Glassman CR, et al. Among authors: kuhns ms. Cell Rep. 2018 Jan 30;22(5):1263-1275. doi: 10.1016/j.celrep.2017.12.104. Cell Rep. 2018. PMID: 29386113 Free PMC article.

10

A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.

Deshpande NR, Uhrlaub JL, Way SS, Nikolich-Žugich J, Kuhns MS. Deshpande NR, et al. Among authors: kuhns ms. PLoS One. 2018 Jun 4;13(6):e0198354. doi: 10.1371/journal.pone.0198354. eCollection 2018. PLoS One. 2018. PMID: 29864157 Free PMC article.

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