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Page 1
Treatment of Clostridium difficile infection using SQ641, a capuramycin analogue, increases post-treatment survival and improves clinical measures of disease in a murine model.
Moore JH 2nd, van Opstal E, Kolling GL, Shin JH, Bogatcheva E, Nikonenko B, Einck L, Phipps AJ, Guerrant RL, Protopopova M, Warren CA. Moore JH 2nd, et al. Among authors: bogatcheva e. J Antimicrob Chemother. 2016 May;71(5):1300-6. doi: 10.1093/jac/dkv479. Epub 2016 Jan 31. J Antimicrob Chemother. 2016. PMID: 26832756 Free PMC article.
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
Nikonenko BV, Reddy VM, Protopopova M, Bogatcheva E, Einck L, Nacy CA. Nikonenko BV, et al. Among authors: bogatcheva e. Antimicrob Agents Chemother. 2009 Jul;53(7):3138-9. doi: 10.1128/AAC.00366-09. Epub 2009 May 4. Antimicrob Agents Chemother. 2009. PMID: 19414567 Free PMC article.
Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis.
Nikonenko B, Reddy VM, Bogatcheva E, Protopopova M, Einck L, Nacy CA. Nikonenko B, et al. Among authors: bogatcheva e. Antimicrob Agents Chemother. 2014;58(1):587-9. doi: 10.1128/AAC.01254-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145521 Free PMC article.
In search of new cures for tuberculosis.
Protopopova M, Bogatcheva E, Nikonenko B, Hundert S, Einck L, Nacy CA. Protopopova M, et al. Among authors: bogatcheva e. Med Chem. 2007 May;3(3):301-16. doi: 10.2174/157340607780620626. Med Chem. 2007. PMID: 17504204 Review.
Identification of SQ609 as a lead compound from a library of dipiperidines.
Bogatcheva E, Hanrahan C, Nikonenko B, de los Santos G, Reddy V, Chen P, Barbosa F, Einck L, Nacy C, Protopopova M. Bogatcheva E, et al. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5353-7. doi: 10.1016/j.bmcl.2011.07.015. Epub 2011 Jul 14. Bioorg Med Chem Lett. 2011. PMID: 21807506 Free PMC article.
Discovery of dipiperidines as new antitubercular agents.
Bogatcheva E, Hanrahan C, Chen P, Gearhart J, Sacksteder K, Einck L, Nacy C, Protopopova M. Bogatcheva E, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):201-5. doi: 10.1016/j.bmcl.2009.10.135. Epub 2009 Nov 4. Bioorg Med Chem Lett. 2010. PMID: 19917527 Free PMC article.
11 results