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Treatment of Clostridium difficile infection using SQ641, a capuramycin analogue, increases post-treatment survival and improves clinical measures of disease in a murine model.
Moore JH 2nd, van Opstal E, Kolling GL, Shin JH, Bogatcheva E, Nikonenko B, Einck L, Phipps AJ, Guerrant RL, Protopopova M, Warren CA. Moore JH 2nd, et al. Among authors: nikonenko b. J Antimicrob Chemother. 2016 May;71(5):1300-6. doi: 10.1093/jac/dkv479. Epub 2016 Jan 31. J Antimicrob Chemother. 2016. PMID: 26832756 Free PMC article.
Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis.
Nikonenko B, Reddy VM, Bogatcheva E, Protopopova M, Einck L, Nacy CA. Nikonenko B, et al. Antimicrob Agents Chemother. 2014;58(1):587-9. doi: 10.1128/AAC.01254-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145521 Free PMC article.
In search of new cures for tuberculosis.
Protopopova M, Bogatcheva E, Nikonenko B, Hundert S, Einck L, Nacy CA. Protopopova M, et al. Among authors: nikonenko b. Med Chem. 2007 May;3(3):301-16. doi: 10.2174/157340607780620626. Med Chem. 2007. PMID: 17504204 Review.
Identification of SQ609 as a lead compound from a library of dipiperidines.
Bogatcheva E, Hanrahan C, Nikonenko B, de los Santos G, Reddy V, Chen P, Barbosa F, Einck L, Nacy C, Protopopova M. Bogatcheva E, et al. Among authors: nikonenko b. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5353-7. doi: 10.1016/j.bmcl.2011.07.015. Epub 2011 Jul 14. Bioorg Med Chem Lett. 2011. PMID: 21807506 Free PMC article.
71 results