Zhang Y - Search Results

1

Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice.

Zhang Y, Liu Y, Walsh M, Bokov A, Ikeno Y, Jang YC, Perez VI, Van Remmen H, Richardson A. Zhang Y, et al. Mech Ageing Dev. 2016 Mar;154:1-8. doi: 10.1016/j.mad.2016.01.005. Epub 2016 Feb 1. Mech Ageing Dev. 2016. PMID: 26839948 Free PMC article.

2

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Zhang Y, et al. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19776219 Free PMC article.

3

Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.

Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H. Zhang Y, et al. Among authors: zhang hm. Free Radic Biol Med. 2013 Jul;60:300-6. doi: 10.1016/j.freeradbiomed.2013.02.026. Epub 2013 Feb 28. Free Radic Biol Med. 2013. PMID: 23459073 Free PMC article.

4

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1^-/^- mice is correlated to increased cellular senescence.

Zhang Y, Unnikrishnan A, Deepa SS, Liu Y, Li Y, Ikeno Y, Sosnowska D, Van Remmen H, Richardson A. Zhang Y, et al. Redox Biol. 2017 Apr;11:30-37. doi: 10.1016/j.redox.2016.10.014. Epub 2016 Nov 2. Redox Biol. 2017. PMID: 27846439 Free PMC article.

5

Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts.

Zhang Y, Zhang HM, Shi Y, Lustgarten M, Li Y, Qi W, Zhang BX, Van Remmen H. Zhang Y, et al. Among authors: zhang bx, zhang hm. Free Radic Biol Med. 2010 Nov 1;49(8):1255-62. doi: 10.1016/j.freeradbiomed.2010.07.006. Epub 2010 Jul 16. Free Radic Biol Med. 2010. PMID: 20638473 Free PMC article.

6

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y. Pérez VI, et al. Among authors: zhang y. J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1286-99. doi: 10.1093/gerona/glr125. Epub 2011 Aug 26. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21873593 Free PMC article.

7

Rapamycin extends life and health in C57BL/6 mice.

Zhang Y, Bokov A, Gelfond J, Soto V, Ikeno Y, Hubbard G, Diaz V, Sloane L, Maslin K, Treaster S, Réndon S, van Remmen H, Ward W, Javors M, Richardson A, Austad SN, Fischer K. Zhang Y, et al. J Gerontol A Biol Sci Med Sci. 2014 Feb;69(2):119-30. doi: 10.1093/gerona/glt056. Epub 2013 May 16. J Gerontol A Biol Sci Med Sci. 2014. PMID: 23682161 Free PMC article.

8

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice.

Zhang Y, Davis C, Sakellariou GK, Shi Y, Kayani AC, Pulliam D, Bhattacharya A, Richardson A, Jackson MJ, McArdle A, Brooks SV, Van Remmen H. Zhang Y, et al. FASEB J. 2013 Sep;27(9):3536-48. doi: 10.1096/fj.13-228130. Epub 2013 May 31. FASEB J. 2013. PMID: 23729587 Free PMC article.

9

Elevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelination.

Hamilton RT, Bhattacharya A, Walsh ME, Shi Y, Wei R, Zhang Y, Rodriguez KA, Buffenstein R, Chaudhuri AR, Van Remmen H. Hamilton RT, et al. Among authors: zhang y. PLoS One. 2013 Jun 4;8(6):e65725. doi: 10.1371/journal.pone.0065725. Print 2013. PLoS One. 2013. PMID: 23750273 Free PMC article.

10

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver.

Fok WC, Bokov A, Gelfond J, Yu Z, Zhang Y, Doderer M, Chen Y, Javors M, Wood WH 3rd, Zhang Y, Becker KG, Richardson A, Pérez VI. Fok WC, et al. Among authors: zhang y. Aging Cell. 2014 Apr;13(2):311-9. doi: 10.1111/acel.12175. Epub 2013 Dec 5. Aging Cell. 2014. PMID: 24304444 Free PMC article.

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