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Improvement of the resistance against early Mycobacterium tuberculosis-infection in the absence of PI3Kγ enzyme is associated with increase of CD4+IL-17+ cells and neutrophils.
Cavalcanti-Neto MP, Prado RQ, Piñeros AR, Sérgio CA, Bertolini TB, Gembre AF, Ramos SG, Bonato VL. Cavalcanti-Neto MP, et al. Among authors: pineros ar. Tuberculosis (Edinb). 2018 Dec;113:1-9. doi: 10.1016/j.tube.2018.08.009. Epub 2018 Aug 23. Tuberculosis (Edinb). 2018. PMID: 30514491
Role of orally induced regulatory T cells in immunotherapy and tolerance.
Bertolini TB, Biswas M, Terhorst C, Daniell H, Herzog RW, Piñeros AR. Bertolini TB, et al. Among authors: pineros ar. Cell Immunol. 2021 Jan;359:104251. doi: 10.1016/j.cellimm.2020.104251. Epub 2020 Nov 14. Cell Immunol. 2021. PMID: 33248367 Free PMC article. Review.
IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice.
Butterfield JSS, Yamada K, Bertolini TB, Syed F, Kumar SRP, Li X, Arisa S, Piñeros AR, Tapia A, Rogers CA, Li N, Rana J, Biswas M, Terhorst C, Kaufman RJ, de Jong YP, Herzog RW. Butterfield JSS, et al. Among authors: pineros ar. Mol Ther. 2022 Dec 7;30(12):3552-3569. doi: 10.1016/j.ymthe.2022.07.005. Epub 2022 Jul 12. Mol Ther. 2022. PMID: 35821634 Free PMC article.
Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells.
Kaczmarek R, Piñeros AR, Patterson PE, Bertolini TB, Perrin GQ, Sherman A, Born J, Arisa S, Arvin MC, Kamocka MM, Martinez MM, Dunn KW, Quinn SM, Morris JJ, Wilhelm AR, Kaisho T, Munoz-Melero M, Biswas M, Kaplan MH, Linnemann AK, George LA, Camire RM, Herzog RW. Kaczmarek R, et al. Among authors: pineros ar. Blood. 2023 Jul 20;142(3):290-305. doi: 10.1182/blood.2022018937. Blood. 2023. PMID: 37192286 Free PMC article.
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