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The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.
Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C. Laubreton D, et al. Among authors: amigorena s. Cancer Immunol Immunother. 2016 Mar;65(3):315-25. doi: 10.1007/s00262-016-1802-0. Epub 2016 Feb 4. Cancer Immunol Immunother. 2016. PMID: 26847142 Free PMC article.
A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.
Sedlik C, Orbach D, Veron P, Schweighoffer E, Colucci F, Gamberale R, Ioan-Facsinay A, Verbeek S, Ricciardi-Castagnoli P, Bonnerot C, Tybulewicz VL, Di Santo J, Amigorena S. Sedlik C, et al. Among authors: amigorena s. J Immunol. 2003 Jan 15;170(2):846-52. doi: 10.4049/jimmunol.170.2.846. J Immunol. 2003. PMID: 12517949
Exosomes bearing HLA-G are released by melanoma cells.
Riteau B, Faure F, Menier C, Viel S, Carosella ED, Amigorena S, Rouas-Freiss N. Riteau B, et al. Among authors: amigorena s. Hum Immunol. 2003 Nov;64(11):1064-72. doi: 10.1016/j.humimm.2003.08.344. Hum Immunol. 2003. PMID: 14602237
Long-lasting cross-presentation of tumor antigen in human DC.
Faure F, Mantegazza A, Sadaka C, Sedlik C, Jotereau F, Amigorena S. Faure F, et al. Among authors: amigorena s. Eur J Immunol. 2009 Feb;39(2):380-90. doi: 10.1002/eji.200838669. Eur J Immunol. 2009. PMID: 19130478 Free article.
Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen.
Sedlik C, Heitzmann A, Viel S, Ait Sarkouh R, Batisse C, Schmidt F, De La Rochere P, Amzallag N, Osinaga E, Oppezzo P, Pritsch O, Sastre-Garau X, Hubert P, Amigorena S, Piaggio E. Sedlik C, et al. Among authors: amigorena s. Oncoimmunology. 2016 Apr 22;5(7):e1171434. doi: 10.1080/2162402X.2016.1171434. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622021 Free PMC article.
Aberrant fucosylation enables breast cancer clusterin to interact with dendritic cell-specific ICAM-grabbing non-integrin (DC-SIGN).
Merlotti A, Malizia AL, Michea P, Bonte PE, Goudot C, Carregal MS, Nuñez N, Sedlik C, Ceballos A, Soumelis V, Amigorena S, Geffner J, Piaggio E, Sabatte J. Merlotti A, et al. Among authors: amigorena s. Oncoimmunology. 2019 Jun 24;8(9):e1629257. doi: 10.1080/2162402X.2019.1629257. eCollection 2019. Oncoimmunology. 2019. PMID: 31428526 Free PMC article.
234 results