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Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
Bertamino A, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Soldovieri MV, Iraci N, Fernandez Carvajal A, de la Torre-Martinez R, Ferrer-Montiel A, Gonzalez Muniz R, Novellino E, Taglialatela M, Campiglia P, Gomez-Monterrey I. Bertamino A, et al. J Med Chem. 2016 Mar 10;59(5):2179-91. doi: 10.1021/acs.jmedchem.5b01914. Epub 2016 Feb 17. J Med Chem. 2016. PMID: 26847872 Free article.
Synthesis and stereochemical structure-activity relationships of 1,3-dioxoperhydropyrido[1,2-c]pyrimidine derivatives: potent and selective cholecystokinin-A receptor antagonists.
Martín-Martínez M, Bartolomé-Nebreda JM, Gómez-Monterrey I, González-Muñiz R, García-López MT, Ballaz S, Barber A, Fortuño A, Del Río J, Herranz R. Martín-Martínez M, et al. J Med Chem. 1997 Oct 10;40(21):3402-7. doi: 10.1021/jm9703247. J Med Chem. 1997. PMID: 9341915
5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK(1) receptor antagonists: structural modifications at the tryptophan domain.
Bartolomé-Nebreda JM, Gómez-Monterrey I, García-López MT, González-Muñiz R, Martín-Martínez M, Ballaz S, Cenarruzabeitia E, LaTorre M, Del Río J, Herranz R. Bartolomé-Nebreda JM, et al. J Med Chem. 1999 Nov 4;42(22):4659-68. doi: 10.1021/jm991078x. J Med Chem. 1999. PMID: 10579828
5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK(1)receptor antagonists: structure-activity relationship studies on the substituent at N2-position.
Bartolomé-Nebreda JM, Patiño-Molina R, Martín-Martínez M, Gómez-Monterrey I, García-López MT, González-Muñiz R, Cenarruzabeitia E, Latorre M, Del Río J, Herranz R. Bartolomé-Nebreda JM, et al. J Med Chem. 2001 Jun 21;44(13):2219-28. doi: 10.1021/jm010813d. J Med Chem. 2001. PMID: 11405658
96 results