Cook GM - Search Results

1

Annotated compound data for modulators of detergent-solubilised or lipid-reconstituted respiratory type II NADH dehydrogenase activity obtained by compound library screening.

Dunn EA, Cook GM, Heikal A. Dunn EA, et al. Among authors: cook gm. Data Brief. 2015 Dec 17;6:275-8. doi: 10.1016/j.dib.2015.12.019. eCollection 2016 Mar. Data Brief. 2015. PMID: 26862571 Free PMC article.

2

Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia.

Berney M, Weimar MR, Heikal A, Cook GM. Berney M, et al. Among authors: cook gm. Mol Microbiol. 2012 May;84(4):664-81. doi: 10.1111/j.1365-2958.2012.08053.x. Epub 2012 Apr 16. Mol Microbiol. 2012. PMID: 22507203 Free article.

3

Bridging the gap between a TB drug and its target.

Cook GM, Heikal A. Cook GM, et al. Sci Transl Med. 2012 Sep 5;4(150):150fs33. doi: 10.1126/scitranslmed.3004816. Sci Transl Med. 2012. PMID: 22956196

4

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation.

Heikal A, Nakatani Y, Dunn E, Weimar MR, Day CL, Baker EN, Lott JS, Sazanov LA, Cook GM. Heikal A, et al. Among authors: cook gm. Mol Microbiol. 2014 Mar;91(5):950-64. doi: 10.1111/mmi.12507. Epub 2014 Jan 21. Mol Microbiol. 2014. PMID: 24444429 Free article.

5

Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.

Dunn EA, Roxburgh M, Larsen L, Smith RA, McLellan AD, Heikal A, Murphy MP, Cook GM. Dunn EA, et al. Among authors: cook gm. Bioorg Med Chem. 2014 Oct 1;22(19):5320-8. doi: 10.1016/j.bmc.2014.07.050. Epub 2014 Aug 7. Bioorg Med Chem. 2014. PMID: 25150092

6

Comparison of lipid and detergent enzyme environments for identifying inhibitors of membrane-bound energy-transducing proteins.

Dunn EA, Cook GM, Heikal A. Dunn EA, et al. Among authors: cook gm. J Microbiol Methods. 2016 Jan;120:41-3. doi: 10.1016/j.mimet.2015.11.012. Epub 2015 Nov 28. J Microbiol Methods. 2016. PMID: 26593449

7

Activation of type II NADH dehydrogenase by quinolinequinones mediates antitubercular cell death.

Heikal A, Hards K, Cheung CY, Menorca A, Timmer MS, Stocker BL, Cook GM. Heikal A, et al. Among authors: cook gm. J Antimicrob Chemother. 2016 Oct;71(10):2840-7. doi: 10.1093/jac/dkw244. Epub 2016 Jun 30. J Antimicrob Chemother. 2016. PMID: 27365187

8

Microarray dataset on the genome-wide expression profile of an M. smegmatis amtR mutant (JR258) compared to M. smegmatis mc²155.

Petridis M, Cook GM. Petridis M, et al. Among authors: cook gm. Data Brief. 2016 Nov 23;10:38-40. doi: 10.1016/j.dib.2016.11.049. eCollection 2017 Feb. Data Brief. 2016. PMID: 27942565 Free PMC article.

9

The mechanism of catalysis by type-II NADH:quinone oxidoreductases.

Blaza JN, Bridges HR, Aragão D, Dunn EA, Heikal A, Cook GM, Nakatani Y, Hirst J. Blaza JN, et al. Among authors: cook gm. Sci Rep. 2017 Jan 9;7:40165. doi: 10.1038/srep40165. Sci Rep. 2017. PMID: 28067272 Free PMC article.

10

Oxidative Phosphorylation as a Target Space for Tuberculosis: Success, Caution, and Future Directions.

Cook GM, Hards K, Dunn E, Heikal A, Nakatani Y, Greening C, Crick DC, Fontes FL, Pethe K, Hasenoehrl E, Berney M. Cook GM, et al. Microbiol Spectr. 2017 Jun;5(3):10.1128/microbiolspec.tbtb2-0014-2016. doi: 10.1128/microbiolspec.TBTB2-0014-2016. Microbiol Spectr. 2017. PMID: 28597820 Free PMC article. Review.

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