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Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates.
Ajdačić V, Senerovic L, Vranić M, Pekmezovic M, Arsic-Arsnijevic V, Veselinovic A, Veselinovic J, Šolaja BA, Nikodinovic-Runic J, Opsenica IM. Ajdačić V, et al. Among authors: opsenica im. Bioorg Med Chem. 2016 Mar 15;24(6):1277-91. doi: 10.1016/j.bmc.2016.01.058. Epub 2016 Feb 2. Bioorg Med Chem. 2016. PMID: 26867487
Tetraoxane antimalarials and their reaction with Fe(II).
Opsenica I, Terzić N, Opsenica D, Angelovski G, Lehnig M, Eilbracht P, Tinant B, Juranić Z, Smith KS, Yang YS, Diaz DS, Smith PL, Milhous WK, Doković D, Solaja BA. Opsenica I, et al. J Med Chem. 2006 Jun 29;49(13):3790-9. doi: 10.1021/jm050966r. J Med Chem. 2006. PMID: 16789736
A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.
Opsenica I, Burnett JC, Gussio R, Opsenica D, Todorović N, Lanteri CA, Sciotti RJ, Gettayacamin M, Basilico N, Taramelli D, Nuss JE, Wanner L, Panchal RG, Solaja BA, Bavari S. Opsenica I, et al. J Med Chem. 2011 Mar 10;54(5):1157-69. doi: 10.1021/jm100938u. Epub 2011 Jan 25. J Med Chem. 2011. PMID: 21265542 Free PMC article.
28 results