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Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes.
Samitas K, Poulos N, Semitekolou M, Morianos I, Tousa S, Economidou E, Robinson DS, Kariyawasam HH, Zervas E, Corrigan CJ, Ying S, Xanthou G, Gaga M. Samitas K, et al. Among authors: tousa s. Eur Respir J. 2016 Mar;47(3):769-82. doi: 10.1183/13993003.00437-2015. Epub 2016 Feb 11. Eur Respir J. 2016. PMID: 26869672 Free article.
Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses.
Tousa S, Semitekolou M, Morianos I, Banos A, Trochoutsou AI, Brodie TM, Poulos N, Samitas K, Kapasa M, Konstantopoulos D, Paraskevopoulos G, Gaga M, Hawrylowicz CM, Sallusto F, Xanthou G. Tousa S, et al. Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2891-E2900. doi: 10.1073/pnas.1616942114. Epub 2017 Mar 20. Proc Natl Acad Sci U S A. 2017. PMID: 28320933 Free PMC article.
Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects.
Vittorakis S, Samitas K, Tousa S, Zervas E, Aggelakopoulou M, Semitekolou M, Panoutsakopoulou V, Xanthou G, Gaga M. Vittorakis S, et al. Among authors: tousa s. Biomed Res Int. 2014;2014:231036. doi: 10.1155/2014/231036. Epub 2014 Apr 28. Biomed Res Int. 2014. PMID: 24877070 Free PMC article. Clinical Trial.
Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand.
Tsoumakidou M, Tousa S, Semitekolou M, Panagiotou P, Panagiotou A, Morianos I, Litsiou E, Trochoutsou AI, Konstantinou M, Potaris K, Footitt J, Mallia P, Zakynthinos S, Johnston SL, Xanthou G. Tsoumakidou M, et al. Among authors: tousa s. J Allergy Clin Immunol. 2014 Oct;134(4):944-954.e8. doi: 10.1016/j.jaci.2014.05.045. Epub 2014 Jul 19. J Allergy Clin Immunol. 2014. PMID: 25051954