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Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K. Yamamoto T, et al. Among authors: tsubota k. Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1003-14. doi: 10.1152/ajpheart.00676.2015. Epub 2016 Feb 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 26873964 Free article.
Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization.
Kaneko H, Anzai T, Morisawa M, Kohno T, Nagai T, Anzai A, Takahashi T, Shimoda M, Sasaki A, Maekawa Y, Yoshimura K, Aoki H, Tsubota K, Yoshikawa T, Okada Y, Ogawa S, Fukuda K. Kaneko H, et al. Among authors: tsubota k. Atherosclerosis. 2011 Aug;217(2):350-7. doi: 10.1016/j.atherosclerosis.2011.03.042. Epub 2011 Apr 8. Atherosclerosis. 2011. PMID: 21530968
Age-related dysfunction of the lacrimal gland and oxidative stress: evidence from the Cu,Zn-superoxide dismutase-1 (Sod1) knockout mice.
Kojima T, Wakamatsu TH, Dogru M, Ogawa Y, Igarashi A, Ibrahim OM, Inaba T, Shimizu T, Noda S, Obata H, Nakamura S, Wakamatsu A, Shirasawa T, Shimazaki J, Negishi K, Tsubota K. Kojima T, et al. Among authors: tsubota k. Am J Pathol. 2012 May;180(5):1879-96. doi: 10.1016/j.ajpath.2012.01.019. Epub 2012 Mar 20. Am J Pathol. 2012. PMID: 22440255
The antiaging approach for the treatment of dry eye.
Tsubota K, Kawashima M, Inaba T, Dogru M, Matsumoto Y, Ishida R, Kaido M, Kojima T, Uchino M, Uchino Y, Ogawa Y, Nakamura S, Higuchi A, Shinmura K, Watanabe M, Kawakita T. Tsubota K, et al. Cornea. 2012 Nov;31 Suppl 1:S3-8. doi: 10.1097/ICO.0b013e31826a05a8. Cornea. 2012. PMID: 23038031 Review.
1,436 results