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Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities.
Yenerall P, Sung T, Palyada K, Qian J, Arat S, Kumpf SW, Wang SW, Biddle K, Esparza C, Chang S, Scott W, Collette W, Winrow TS, Affolter T, Shirai N, Thibault S, Wang J, Liu L, Bauchmann M, Frey J, Steyn S, Sacaan A, Vitsky A, Ahn Y, Paul T, Lum L, Oyer J, Yang A, Hu W. Yenerall P, et al. Among authors: vitsky a. Toxicol Sci. 2023 Jun 28;194(1):53-69. doi: 10.1093/toxsci/kfad049. Toxicol Sci. 2023. PMID: 37228089 Free PMC article.
Principles for Assessing Adversity in Toxicologic Clinical Pathology.
Ramaiah L, Tomlinson L, Tripathi NK, Cregar LC, Vitsky A, Beust BV, Barlow VG, Reagan WJ, Ennulat D. Ramaiah L, et al. Among authors: vitsky a. Toxicol Pathol. 2017 Feb;45(2):260-266. doi: 10.1177/0192623316681646. Epub 2017 Jan 5. Toxicol Pathol. 2017. PMID: 28056663 Review.
Session 5: Protein Degraders.
Palyada K, Hukkanen R, Leuenroth-Quinn S, Vitsky A, Peterson R, Stamp K, Hoover C, Volak L. Palyada K, et al. Among authors: vitsky a. Toxicol Pathol. 2024 Dec 11:1926233241300452. doi: 10.1177/01926233241300452. Online ahead of print. Toxicol Pathol. 2024. PMID: 39660628
29 results