Chon H - Search Results

1

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Pokatayev V, Hasin N, Chon H, Cerritelli SM, Sakhuja K, Ward JM, Morris HD, Yan N, Crouch RJ. Pokatayev V, et al. Among authors: chon h. J Exp Med. 2016 Mar 7;213(3):329-36. doi: 10.1084/jem.20151464. Epub 2016 Feb 15. J Exp Med. 2016. PMID: 26880576 Free PMC article.

2

Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.

Uehara R, Cerritelli SM, Hasin N, Sakhuja K, London M, Iranzo J, Chon H, Grinberg A, Crouch RJ. Uehara R, et al. Among authors: chon h. Cell Rep. 2018 Oct 30;25(5):1135-1145.e5. doi: 10.1016/j.celrep.2018.10.019. Cell Rep. 2018. PMID: 30380406 Free PMC article.

3

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.

Chon H, Vassilev A, DePamphilis ML, Zhao Y, Zhang J, Burgers PM, Crouch RJ, Cerritelli SM. Chon H, et al. Nucleic Acids Res. 2009 Jan;37(1):96-110. doi: 10.1093/nar/gkn913. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015152 Free PMC article.

4

The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects.

Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M. Figiel M, et al. Among authors: chon h. J Biol Chem. 2011 Mar 25;286(12):10540-50. doi: 10.1074/jbc.M110.181974. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177858 Free PMC article.

5

Molecular biology. A new twist for topoisomerase.

Cerritelli SM, Chon H, Crouch RJ. Cerritelli SM, et al. Among authors: chon h. Science. 2011 Jun 24;332(6037):1510-1. doi: 10.1126/science.1208450. Science. 2011. PMID: 21700860 Free PMC article. No abstract available.

6

RNase H2 roles in genome integrity revealed by unlinking its activities.

Chon H, Sparks JL, Rychlik M, Nowotny M, Burgers PM, Crouch RJ, Cerritelli SM. Chon H, et al. Nucleic Acids Res. 2013 Mar 1;41(5):3130-43. doi: 10.1093/nar/gkt027. Epub 2013 Jan 25. Nucleic Acids Res. 2013. PMID: 23355612 Free PMC article.

7

R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching.

Maul RW, Chon H, Sakhuja K, Cerritelli SM, Gugliotti LA, Gearhart PJ, Crouch RJ. Maul RW, et al. Among authors: chon h. J Mol Biol. 2017 Oct 27;429(21):3255-3263. doi: 10.1016/j.jmb.2016.12.020. Epub 2017 Jan 6. J Mol Biol. 2017. PMID: 28065739 Free PMC article.

8

Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

Rychlik MP, Chon H, Cerritelli SM, Klimek P, Crouch RJ, Nowotny M. Rychlik MP, et al. Among authors: chon h. Mol Cell. 2010 Nov 24;40(4):658-70. doi: 10.1016/j.molcel.2010.11.001. Mol Cell. 2010. PMID: 21095591 Free PMC article.

9

Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.

Malfatti MC, Balachander S, Antoniali G, Koh KD, Saint-Pierre C, Gasparutto D, Chon H, Crouch RJ, Storici F, Tell G. Malfatti MC, et al. Among authors: chon h. Nucleic Acids Res. 2017 Nov 2;45(19):11193-11212. doi: 10.1093/nar/gkx723. Nucleic Acids Res. 2017. PMID: 28977421 Free PMC article.

10

RNase H2-initiated ribonucleotide excision repair.

Sparks JL, Chon H, Cerritelli SM, Kunkel TA, Johansson E, Crouch RJ, Burgers PM. Sparks JL, et al. Among authors: chon h. Mol Cell. 2012 Sep 28;47(6):980-6. doi: 10.1016/j.molcel.2012.06.035. Epub 2012 Aug 2. Mol Cell. 2012. PMID: 22864116 Free PMC article.

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