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Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.
Sunami Y, Ringelhan M, Kokai E, Lu M, O'Connor T, Lorentzen A, Weber A, Rodewald AK, Müllhaupt B, Terracciano L, Gul S, Wissel S, Leithäuser F, Krappmann D, Riedl P, Hartmann D, Schirmbeck R, Strnad P, Hüser N, Kleeff J, Friess H, Schmid RM, Geisler F, Wirth T, Heikenwalder M. Sunami Y, et al. Among authors: strnad p. Hepatology. 2016 May;63(5):1592-607. doi: 10.1002/hep.28435. Epub 2016 Mar 4. Hepatology. 2016. PMID: 26892811 Free article.
Telomerase gene mutations are associated with cirrhosis formation.
Hartmann D, Srivastava U, Thaler M, Kleinhans KN, N'kontchou G, Scheffold A, Bauer K, Kratzer RF, Kloos N, Katz SF, Song Z, Begus-Nahrmann Y, Kleger A, von Figura G, Strnad P, Lechel A, Günes C, Potthoff A, Deterding K, Wedemeyer H, Ju Z, Song G, Xiao F, Gillen S, Schrezenmeier H, Mertens T, Ziol M, Friess H, Jarek M, Manns MP, Beaugrand M, Rudolph KL. Hartmann D, et al. Among authors: strnad p. Hepatology. 2011 May;53(5):1608-17. doi: 10.1002/hep.24217. Hepatology. 2011. PMID: 21520174
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.
Sunami Y, Leithäuser F, Gul S, Fiedler K, Güldiken N, Espenlaub S, Holzmann KH, Hipp N, Sindrilaru A, Luedde T, Baumann B, Wissel S, Kreppel F, Schneider M, Scharffetter-Kochanek K, Kochanek S, Strnad P, Wirth T. Sunami Y, et al. Among authors: strnad p. Hepatology. 2012 Sep;56(3):1117-28. doi: 10.1002/hep.25711. Epub 2012 Jul 10. Hepatology. 2012. PMID: 22407857
CHOP-mediated hepcidin suppression modulates hepatic iron load.
Mueller K, Sunami Y, Stuetzle M, Guldiken N, Kucukoglu O, Mueller S, Kulaksiz H, Schwarz P, Strnad P. Mueller K, et al. Among authors: strnad p. J Pathol. 2013 Dec;231(4):532-42. doi: 10.1002/path.4221. Epub 2013 Oct 15. J Pathol. 2013. PMID: 23749468
The role of telomeres in liver disease.
Sunami Y, von Figura G, Kleger A, Strnad P, Hüser N, Hartmann D. Sunami Y, et al. Among authors: strnad p. Prog Mol Biol Transl Sci. 2014;125:159-72. doi: 10.1016/B978-0-12-397898-1.00007-4. Prog Mol Biol Transl Sci. 2014. PMID: 24993702 Review.
304 results