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Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Correia JC, et al. Among authors: sinha i. Mol Metab. 2015 Sep 26;4(12):891-902. doi: 10.1016/j.molmet.2015.09.005. eCollection 2015 Dec. Mol Metab. 2015. PMID: 26909306 Free PMC article.
RING finger protein 31 promotes p53 degradation in breast cancer cells.
Zhu J, Zhao C, Zhuang T, Jonsson P, Sinha I, Williams C, Strömblad S, Dahlman-Wright K. Zhu J, et al. Among authors: sinha i. Oncogene. 2016 Apr 14;35(15):1955-64. doi: 10.1038/onc.2015.260. Epub 2015 Jul 6. Oncogene. 2016. PMID: 26148235 Free PMC article.
Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes.
Martínez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Martínez-Redondo V, et al. Among authors: sinha i. J Biol Chem. 2016 Jul 15;291(29):15169-84. doi: 10.1074/jbc.M115.705822. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231350 Free PMC article.
Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.
Jia M, Andreassen T, Jensen L, Bathen TF, Sinha I, Gao H, Zhao C, Haldosen LA, Cao Y, Girnita L, Moestue SA, Dahlman-Wright K. Jia M, et al. Among authors: sinha i. Cancer Res. 2016 Oct 1;76(19):5634-5646. doi: 10.1158/0008-5472.CAN-15-2910. Epub 2016 Jul 25. Cancer Res. 2016. PMID: 27457520
411 results