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Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice.
Forkuo GS, Kim H, Thanawala VJ, Al-Sawalha N, Valdez D, Joshi R, Parra S, Pera T, Gonnella PA, Knoll BJ, Walker JK, Penn RB, Bond RA. Forkuo GS, et al. Among authors: knoll bj. Am J Respir Cell Mol Biol. 2016 Aug;55(2):234-42. doi: 10.1165/rcmb.2015-0373OC. Am J Respir Cell Mol Biol. 2016. PMID: 26909542 Free PMC article.
β-Blockers have differential effects on the murine asthma phenotype.
Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P, Bond RA. Thanawala VJ, et al. Among authors: knoll bj. Br J Pharmacol. 2015 Oct;172(20):4833-46. doi: 10.1111/bph.13253. Epub 2015 Oct 13. Br J Pharmacol. 2015. PMID: 26211486 Free PMC article.
β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility.
Nguyen LP, Al-Sawalha NA, Parra S, Pokkunuri I, Omoluabi O, Okulate AA, Windham Li E, Hazen M, Gonzalez-Granado JM, Daly CJ, McGrath JC, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA. Nguyen LP, et al. Among authors: knoll bj. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9163-E9171. doi: 10.1073/pnas.1710196114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073113 Free PMC article.
56 results