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Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity.
Bartz R, Fukuchi K, Ohtsuka T, Lange T, Gruner K, Watanabe I, Hayashi S, Oda Y, Kawaida R, Komori H, Kashimoto Y, Wirtz P, Mayer JA, Redondo-Müller M, Saito S, Takahashi M, Hanzawa H, Imai E, Martinez A, Hanai M, Häussinger D, Chapman RW, Agatsuma T, Bange J, Abraham R. Bartz R, et al. Among authors: fukuchi k. Mol Cancer Ther. 2019 Oct;18(10):1832-1843. doi: 10.1158/1535-7163.MCT-18-0048. Epub 2019 Jul 26. Mol Cancer Ther. 2019. PMID: 31350344
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals.
Fukuchi K, Nanai K, Yuita H, Maru C, Tsukada J, Ishigami M, Nagai Y, Nakano Y, Yoshimura C, Yoneda K, Amano M, Nakamura K, Oda Y, Nishigohri H, Yamamoto S, Ohnishi-Totoki Y, Inaki K, Komori H, Nakano R, Kanari Y, Nishida A, Matsui Y, Funo S, Takahashi S, Ohtsuka T, Agatsuma T. Fukuchi K, et al. J Oncol. 2022 Nov 4;2022:3552793. doi: 10.1155/2022/3552793. eCollection 2022. J Oncol. 2022. PMID: 36385956 Free PMC article.
Development of hydrophobic tag purifying monophosphorylated RNA for chemical synthesis of capped mRNA and enzymatic synthesis of circular mRNA.
Ototake M, Inagaki M, Kimura S, Onda K, Tada M, Kawaguchi D, Murase H, Fukuchi K, Gao Y, Kokubo K, Acharyya S, Meng Z, Ishida T, Kawasaki T, Abe N, Hashiya F, Kimura Y, Abe H. Ototake M, et al. Among authors: fukuchi k. Nucleic Acids Res. 2024 Oct 17:gkae847. doi: 10.1093/nar/gkae847. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39414255
Development of radioiodine-labeled mequitazine for evaluation of hepatic CYP2D activity.
Mizutani A, Kobayashi M, Nishi K, Fujita KI, Takahashi K, Muranaka Y, Sato K, Kitamura M, Suzuki C, Nishii R, Shikano N, Magata Y, Ishida Y, Kunishima M, Fukuchi K, Kawai K. Mizutani A, et al. Among authors: fukuchi k. Front Pharmacol. 2024 Jun 19;15:1397288. doi: 10.3389/fphar.2024.1397288. eCollection 2024. Front Pharmacol. 2024. PMID: 38962307 Free PMC article.
360 results