Aghajanian GK - Search Results

1

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.

Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Duman RS, et al. Among authors: aghajanian gk. Nat Med. 2016 Mar;22(3):238-49. doi: 10.1038/nm.4050. Nat Med. 2016. PMID: 26937618 Free PMC article.

2

Signaling pathways underlying the rapid antidepressant actions of ketamine.

Duman RS, Li N, Liu RJ, Duric V, Aghajanian G. Duman RS, et al. Neuropharmacology. 2012 Jan;62(1):35-41. doi: 10.1016/j.neuropharm.2011.08.044. Epub 2011 Sep 2. Neuropharmacology. 2012. PMID: 21907221 Free PMC article. Review.

3

Synaptic dysfunction in depression: potential therapeutic targets.

Duman RS, Aghajanian GK. Duman RS, et al. Among authors: aghajanian gk. Science. 2012 Oct 5;338(6103):68-72. doi: 10.1126/science.1222939. Science. 2012. PMID: 23042884 Free PMC article. Review.

4

Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β.

Duman RS, Aghajanian GK. Duman RS, et al. Among authors: aghajanian gk. Neuropsychopharmacology. 2014 Jan;39(1):233. doi: 10.1038/npp.2013.217. Neuropsychopharmacology. 2014. PMID: 24317309 Free PMC article. No abstract available.

5

REDD1 is essential for stress-induced synaptic loss and depressive behavior.

Ota KT, Liu RJ, Voleti B, Maldonado-Aviles JG, Duric V, Iwata M, Dutheil S, Duman C, Boikess S, Lewis DA, Stockmeier CA, DiLeone RJ, Rex C, Aghajanian GK, Duman RS. Ota KT, et al. Among authors: aghajanian gk. Nat Med. 2014 May;20(5):531-5. doi: 10.1038/nm.3513. Epub 2014 Apr 13. Nat Med. 2014. PMID: 24728411 Free PMC article.

6

Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.

Li N, Liu RJ, Dwyer JM, Banasr M, Lee B, Son H, Li XY, Aghajanian G, Duman RS. Li N, et al. Biol Psychiatry. 2011 Apr 15;69(8):754-61. doi: 10.1016/j.biopsych.2010.12.015. Epub 2011 Feb 3. Biol Psychiatry. 2011. PMID: 21292242 Free PMC article.

7

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses.

Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS. Voleti B, et al. Biol Psychiatry. 2013 Nov 15;74(10):742-9. doi: 10.1016/j.biopsych.2013.04.025. Epub 2013 Jun 14. Biol Psychiatry. 2013. PMID: 23751205 Free PMC article.

8

GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.

Liu RJ, Duman C, Kato T, Hare B, Lopresto D, Bang E, Burgdorf J, Moskal J, Taylor J, Aghajanian G, Duman RS. Liu RJ, et al. Neuropsychopharmacology. 2017 May;42(6):1231-1242. doi: 10.1038/npp.2016.202. Epub 2016 Sep 16. Neuropsychopharmacology. 2017. PMID: 27634355 Free PMC article.

9

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.

Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS. Li N, et al. Science. 2010 Aug 20;329(5994):959-64. doi: 10.1126/science.1190287. Science. 2010. PMID: 20724638 Free PMC article.

10

Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.

Liu RJ, Lee FS, Li XY, Bambico F, Duman RS, Aghajanian GK. Liu RJ, et al. Among authors: aghajanian gk. Biol Psychiatry. 2012 Jun 1;71(11):996-1005. doi: 10.1016/j.biopsych.2011.09.030. Epub 2011 Oct 29. Biol Psychiatry. 2012. PMID: 22036038 Free PMC article.

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