Jemth P - Search Results

1

Ligand binding to the PDZ domains of postsynaptic density protein 95.

Toto A, Pedersen SW, Karlsson OA, Moran GE, Andersson E, Chi CN, Strømgaard K, Gianni S, Jemth P. Toto A, et al. Among authors: jemth p. Protein Eng Des Sel. 2016 May;29(5):169-75. doi: 10.1093/protein/gzw004. Epub 2016 Mar 2. Protein Eng Des Sel. 2016. PMID: 26941280

2

Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation.

Jemth P, Gianni S, Day R, Li B, Johnson CM, Daggett V, Fersht AR. Jemth P, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6450-5. doi: 10.1073/pnas.0401732101. Epub 2004 Apr 19. Proc Natl Acad Sci U S A. 2004. PMID: 15096617 Free PMC article.

3

The structure of the major transition state for folding of an FF domain from experiment and simulation.

Jemth P, Day R, Gianni S, Khan F, Allen M, Daggett V, Fersht AR. Jemth P, et al. J Mol Biol. 2005 Jul 8;350(2):363-78. doi: 10.1016/j.jmb.2005.04.067. J Mol Biol. 2005. PMID: 15935381

4

Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding.

White GW, Gianni S, Grossmann JG, Jemth P, Fersht AR, Daggett V. White GW, et al. Among authors: jemth p. J Mol Biol. 2005 Jul 22;350(4):757-75. doi: 10.1016/j.jmb.2005.05.005. J Mol Biol. 2005. PMID: 15967458

5

The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism.

Gianni S, Engström A, Larsson M, Calosci N, Malatesta F, Eklund L, Ngang CC, Travaglini-Allocatelli C, Jemth P. Gianni S, et al. Among authors: jemth p. J Biol Chem. 2005 Oct 14;280(41):34805-12. doi: 10.1074/jbc.M506017200. Epub 2005 Jul 27. J Biol Chem. 2005. PMID: 16049001 Free article.

6

Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain.

Chi CN, Engström A, Gianni S, Larsson M, Jemth P. Chi CN, et al. Among authors: jemth p. J Biol Chem. 2006 Dec 1;281(48):36811-8. doi: 10.1074/jbc.M607883200. Epub 2006 Oct 2. J Biol Chem. 2006. PMID: 17018532 Free article.

7

Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering.

Gianni S, Walma T, Arcovito A, Calosci N, Bellelli A, Engström A, Travaglini-Allocatelli C, Brunori M, Jemth P, Vuister GW. Gianni S, et al. Among authors: jemth p. Structure. 2006 Dec;14(12):1801-9. doi: 10.1016/j.str.2006.10.010. Structure. 2006. PMID: 17161370 Free article.

8

A PDZ domain recapitulates a unifying mechanism for protein folding.

Gianni S, Geierhaas CD, Calosci N, Jemth P, Vuister GW, Travaglini-Allocatelli C, Vendruscolo M, Brunori M. Gianni S, et al. Among authors: jemth p. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):128-33. doi: 10.1073/pnas.0602770104. Epub 2006 Dec 19. Proc Natl Acad Sci U S A. 2007. PMID: 17179214 Free PMC article.

9

An on-pathway intermediate in the folding of a PDZ domain.

Ivarsson Y, Travaglini-Allocatelli C, Jemth P, Malatesta F, Brunori M, Gianni S. Ivarsson Y, et al. Among authors: jemth p. J Biol Chem. 2007 Mar 23;282(12):8568-72. doi: 10.1074/jbc.M611026200. Epub 2007 Jan 24. J Biol Chem. 2007. PMID: 17251182 Free article.

10

A conserved folding mechanism for PDZ domains.

Chi CN, Gianni S, Calosci N, Travaglini-Allocatelli C, Engström K, Jemth P. Chi CN, et al. Among authors: jemth p. FEBS Lett. 2007 Mar 20;581(6):1109-13. doi: 10.1016/j.febslet.2007.02.011. Epub 2007 Feb 15. FEBS Lett. 2007. PMID: 17316619 Free article.

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