Tian H - Search Results

1

Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine and 1H-pyrazolo[3,4-b]pyridine derivatives as c-Met inhibitors.

Liu N, Wang Y, Huang G, Ji C, Fan W, Li H, Cheng Y, Tian H. Liu N, et al. Among authors: tian h. Bioorg Chem. 2016 Apr;65:146-58. doi: 10.1016/j.bioorg.2016.02.009. Epub 2016 Mar 2. Bioorg Chem. 2016. PMID: 26950400

2

Current Development Status of MEK Inhibitors.

Cheng Y, Tian H. Cheng Y, et al. Among authors: tian h. Molecules. 2017 Sep 26;22(10):1551. doi: 10.3390/molecules22101551. Molecules. 2017. PMID: 28954413 Free PMC article. Review.

3

The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.

Dong Y, Cheng Y, Hou Q, Wu J, Li D, Tian H. Dong Y, et al. Among authors: tian h. Oxid Med Cell Longev. 2018 Jul 4;2018:3920147. doi: 10.1155/2018/3920147. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30116481 Free PMC article.

4

A benzoxazole compound as a novel MEK inhibitor for the treatment of RAS/RAF mutant cancer.

Cheng Y, Wang X, Xia X, Zhang W, Tian H. Cheng Y, et al. Among authors: tian h. Int J Cancer. 2019 Jul 15;145(2):586-596. doi: 10.1002/ijc.32119. Epub 2019 Jan 28. Int J Cancer. 2019. PMID: 30628057

5

The protective effects of XH-105 against radiation-induced intestinal injury.

Cheng Y, Dong Y, Hou Q, Wu J, Zhang W, Tian H, Li D. Cheng Y, et al. Among authors: tian h. J Cell Mol Med. 2019 Mar;23(3):2238-2247. doi: 10.1111/jcmm.14159. Epub 2019 Jan 20. J Cell Mol Med. 2019. PMID: 30663222 Free PMC article.

6

A New Compound with Increased Antitumor Activity by Cotargeting MEK and Pim-1.

Li Y, Cheng Y, Zhang M, He X, Kong L, Zhou K, Zhou Y, Li L, Tian H, Song X, Cui Y. Li Y, et al. Among authors: tian h. iScience. 2020 Jul 24;23(7):101254. doi: 10.1016/j.isci.2020.101254. Epub 2020 Jun 10. iScience. 2020. PMID: 32585592 Free PMC article.

7

Polycysteine as a new type of radio-protector ameliorated tissue injury through inhibiting ferroptosis in mice.

Zhang J, Li K, Zhang Q, Zhu Z, Huang G, Tian H. Zhang J, et al. Among authors: tian h. Cell Death Dis. 2021 Feb 18;12(2):195. doi: 10.1038/s41419-021-03479-0. Cell Death Dis. 2021. PMID: 33602915 Free PMC article.

8

Neuroprotective Effect of a New Free Radical Scavenger HL-008 in an Ischemia-Reperfusion Injury Rat Model.

Liu Y, Cheng Y, Zhang W, Tian H. Liu Y, et al. Among authors: tian h. Neuroscience. 2021 Jun 15;465:105-115. doi: 10.1016/j.neuroscience.2021.04.012. Epub 2021 Apr 27. Neuroscience. 2021. PMID: 33915200

9

Phase I pharmacokinetic study of an oral, small-molecule MEK inhibitor tunlametinib in patients with advanced NRAS mutant melanoma.

Zhao Q, Wang T, Wang H, Cui C, Zhong W, Fu D, Xi W, Si L, Guo J, Cheng Y, Tian H, Hu P. Zhao Q, et al. Among authors: tian h. Front Pharmacol. 2022 Nov 1;13:1039416. doi: 10.3389/fphar.2022.1039416. eCollection 2022. Front Pharmacol. 2022. PMID: 36386136 Free PMC article.

10

Preclinical characterization of tunlametinib, a novel, potent, and selective MEK inhibitor.

Liu Y, Cheng Y, Huang G, Xia X, Wang X, Tian H. Liu Y, et al. Among authors: tian h. Front Pharmacol. 2023 Sep 21;14:1271268. doi: 10.3389/fphar.2023.1271268. eCollection 2023. Front Pharmacol. 2023. PMID: 37808191 Free PMC article.

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