McGinty RK - Search Results

1

Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.

Girish TS, McGinty RK, Tan S. Girish TS, et al. Among authors: mcginty rk. J Mol Biol. 2016 Apr 24;428(8):1531-43. doi: 10.1016/j.jmb.2016.02.025. Epub 2016 Mar 4. J Mol Biol. 2016. PMID: 26953260 Free PMC article.

2

The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation.

Kim J, Kim JA, McGinty RK, Nguyen UT, Muir TW, Allis CD, Roeder RG. Kim J, et al. Among authors: mcginty rk. Mol Cell. 2013 Mar 28;49(6):1121-33. doi: 10.1016/j.molcel.2013.01.034. Epub 2013 Feb 28. Mol Cell. 2013. PMID: 23453808 Free PMC article.

3

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.

McGinty RK, Henrici RC, Tan S. McGinty RK, et al. Nature. 2014 Oct 30;514(7524):591-6. doi: 10.1038/nature13890. Nature. 2014. PMID: 25355358 Free PMC article.

4

Nucleosome structure and function.

McGinty RK, Tan S. McGinty RK, et al. Chem Rev. 2015 Mar 25;115(6):2255-73. doi: 10.1021/cr500373h. Epub 2014 Dec 12. Chem Rev. 2015. PMID: 25495456 Free PMC article. Review. No abstract available.

5

Recognition of the nucleosome by chromatin factors and enzymes.

McGinty RK, Tan S. McGinty RK, et al. Curr Opin Struct Biol. 2016 Apr;37:54-61. doi: 10.1016/j.sbi.2015.11.014. Epub 2016 Jan 5. Curr Opin Struct Biol. 2016. PMID: 26764865 Free PMC article. Review.

6

Preparation, Crystallization, and Structure Determination of Chromatin Enzyme/Nucleosome Complexes.

McGinty RK, Makde RD, Tan S. McGinty RK, et al. Methods Enzymol. 2016;573:43-65. doi: 10.1016/bs.mie.2016.01.003. Epub 2016 Feb 16. Methods Enzymol. 2016. PMID: 27372748 Free PMC article.

7

Principles of nucleosome recognition by chromatin factors and enzymes.

McGinty RK, Tan S. McGinty RK, et al. Curr Opin Struct Biol. 2021 Dec;71:16-26. doi: 10.1016/j.sbi.2021.05.006. Epub 2021 Jun 28. Curr Opin Struct Biol. 2021. PMID: 34198054 Free PMC article. Review.

8

DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding.

Spangler CJ, Yadav SP, Li D, Geil CN, Smith CB, Wang GG, Lee TH, McGinty RK. Spangler CJ, et al. Among authors: mcginty rk. Cell Rep. 2022 Feb 15;38(7):110369. doi: 10.1016/j.celrep.2022.110369. Cell Rep. 2022. PMID: 35172132 Free PMC article.

9

Determination of Histone Methyltransferase Structures in Complex with the Nucleosome by Cryogenic Electron Microscopy.

Spangler CJ, McGinty RK. Spangler CJ, et al. Among authors: mcginty rk. Methods Mol Biol. 2022;2529:149-168. doi: 10.1007/978-1-0716-2481-4_8. Methods Mol Biol. 2022. PMID: 35733015 Free PMC article.

10

Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.

Anderson CJ, Baird MR, Hsu A, Barbour EH, Koyama Y, Borgnia MJ, McGinty RK. Anderson CJ, et al. Among authors: mcginty rk. Cell Rep. 2019 Feb 12;26(7):1681-1690.e5. doi: 10.1016/j.celrep.2019.01.058. Cell Rep. 2019. PMID: 30759380 Free PMC article.

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