Shaw J - Search Results

1

The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase.

Kumar N, Nakagawa P, Janic B, Romero CA, Worou ME, Monu SR, Peterson EL, Shaw J, Valeriote F, Ongeri EM, Niyitegeka JM, Rhaleb NE, Carretero OA. Kumar N, et al. Among authors: shaw j. Am J Physiol Renal Physiol. 2016 May 15;310(10):F1026-34. doi: 10.1152/ajprenal.00562.2015. Epub 2016 Mar 9. Am J Physiol Renal Physiol. 2016. PMID: 26962108 Free PMC article.

2

Development and validation of a rapid method for the detection of latrunculol A in plasma.

Shaw J, Valeriote FA, Media J, Johnson TA, Amagata T, Tenney K, Crews P. Shaw J, et al. Anal Bioanal Chem. 2010 Mar;396(5):1741-4. doi: 10.1007/s00216-009-3385-5. Epub 2009 Dec 31. Anal Bioanal Chem. 2010. PMID: 20043220 Free PMC article.

3

The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo.

Shaw J, Chen B, Huang WH, Lee AR, Media J, Valeriote FA. Shaw J, et al. J Exp Ther Oncol. 2011;9(2):129-37. J Exp Ther Oncol. 2011. PMID: 21699020

4

Using a simple HPLC approach to identify the enzymatic products of UTL-5g, a small molecule TNF-α inhibitor, from porcine esterase and from rabbit esterase.

Swartz K, Zhang Y, Valeriote F, Chen B, Shaw J. Swartz K, et al. Among authors: shaw j. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 1;940:1-6. doi: 10.1016/j.jchromb.2013.09.021. Epub 2013 Sep 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 24126042 Free PMC article.

5

In vitro metabolism and drug-drug interaction potential of UTL-5g, a novel chemo- and radioprotective agent.

Wu J, Shaw J, Dubaisi S, Valeriote F, Li J. Wu J, et al. Among authors: shaw j. Drug Metab Dispos. 2014 Dec;42(12):2058-67. doi: 10.1124/dmd.114.060095. Epub 2014 Sep 23. Drug Metab Dispos. 2014. PMID: 25249693 Free PMC article.

6

Synthesis and Biological Evaluation of Novel N-phenyl-5-carboxamidyl Isoxazoles as Potential Chemotherapeutic Agents for Colon Cancer.

Shaw J, Chen B, Bourgault JP, Jiang H, Kumar N, Mishra J, Valeriote FA, Media J, Bobbitt K, Pietraszkiewicz H, Edelstein M, Andreana PR. Shaw J, et al. Am J Biomed Sci. 2012;4(1):14-25. doi: 10.5099/aj120100014. Am J Biomed Sci. 2012. PMID: 25285182 Free PMC article.

7

A liquid chromatography with tandem mass spectrometry method for simultaneous determination of UTL-5g and its metabolites in human plasma.

Shaw J, Wiegand R, Wu J, Bao X, Valeriote F, Li J. Shaw J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jun 1;991:92-8. doi: 10.1016/j.jchromb.2015.04.015. Epub 2015 Apr 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 25955381 Free PMC article.

8

The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling.

Deeb D, Gao X, Liu Y, Zhang Y, Shaw J, Valeriote FA, Gautam SC. Deeb D, et al. Among authors: shaw j. Int J Oncol. 2016 Sep;49(3):1139-47. doi: 10.3892/ijo.2016.3587. Epub 2016 Jun 29. Int J Oncol. 2016. PMID: 27573873

9

Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.

Liu Y, Gao X, Deeb D, Zhang Y, Shaw J, Valeriote FA, Gautam SC. Liu Y, et al. Among authors: shaw j. J Exp Ther Oncol. 2016 Nov;11(4):251-260. J Exp Ther Oncol. 2016. PMID: 27849335

10

Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.

Carruthers NJ, Stemmer PM, Chen B, Valeriote F, Gao X, Guatam SC, Shaw J. Carruthers NJ, et al. Among authors: shaw j. Eur J Pharmacol. 2017 Sep 15;811:66-73. doi: 10.1016/j.ejphar.2017.05.049. Epub 2017 May 31. Eur J Pharmacol. 2017. PMID: 28576409 Free PMC article.

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