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Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.
Leppkes M, Maueröder C, Hirth S, Nowecki S, Günther C, Billmeier U, Paulus S, Biermann M, Munoz LE, Hoffmann M, Wildner D, Croxford AL, Waisman A, Mowen K, Jenne DE, Krenn V, Mayerle J, Lerch MM, Schett G, Wirtz S, Neurath MF, Herrmann M, Becker C. Leppkes M, et al. Among authors: croxford al. Nat Commun. 2016 Mar 11;7:10973. doi: 10.1038/ncomms10973. Nat Commun. 2016. PMID: 26964500 Free PMC article.
Does dietary salt induce autoimmunity?
Croxford AL, Waisman A, Becher B. Croxford AL, et al. Cell Res. 2013 Jul;23(7):872-3. doi: 10.1038/cr.2013.65. Epub 2013 May 7. Cell Res. 2013. PMID: 23649312 Free PMC article.
Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease.
Karbach S, Croxford AL, Oelze M, Schüler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reißig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E, Wenzel P, Waisman A, Münzel T. Karbach S, et al. Among authors: croxford al. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2658-68. doi: 10.1161/ATVBAHA.114.304108. Epub 2014 Oct 23. Arterioscler Thromb Vasc Biol. 2014. PMID: 25341795
Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts.
Uluçkan Ö, Jimenez M, Karbach S, Jeschke A, Graña O, Keller J, Busse B, Croxford AL, Finzel S, Koenders M, van den Berg W, Schinke T, Amling M, Waisman A, Schett G, Wagner EF. Uluçkan Ö, et al. Among authors: croxford al. Sci Transl Med. 2016 Mar 16;8(330):330ra37. doi: 10.1126/scitranslmed.aad8996. Epub 2016 Mar 16. Sci Transl Med. 2016. PMID: 27089206
Genetic proof for the transient nature of the Th17 phenotype.
Kurschus FC, Croxford AL, Heinen AP, Wörtge S, Ielo D, Waisman A. Kurschus FC, et al. Among authors: croxford al. Eur J Immunol. 2010 Dec;40(12):3336-46. doi: 10.1002/eji.201040755. Eur J Immunol. 2010. PMID: 21110317 Free article.
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells.
Heink S, Yogev N, Garbers C, Herwerth M, Aly L, Gasperi C, Husterer V, Croxford AL, Möller-Hackbarth K, Bartsch HS, Sotlar K, Krebs S, Regen T, Blum H, Hemmer B, Misgeld T, Wunderlich TF, Hidalgo J, Oukka M, Rose-John S, Schmidt-Supprian M, Waisman A, Korn T. Heink S, et al. Among authors: croxford al. Nat Immunol. 2017 Jan;18(1):74-85. doi: 10.1038/ni.3632. Epub 2016 Nov 28. Nat Immunol. 2017. PMID: 27893700 Free PMC article.
38 results