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MG53 permeates through blood-brain barrier to protect ischemic brain injury.
Yao Y, Zhang B, Zhu H, Li H, Han Y, Chen K, Wang Z, Zeng J, Liu Y, Wang X, Li Y, He D, Lin P, Zhou X, Park KH, Bian Z, Chen Z, Gong N, Tan T, Zhou J, Zhang M, Ma J, Zeng C. Yao Y, et al. Among authors: lin p. Oncotarget. 2016 Apr 19;7(16):22474-85. doi: 10.18632/oncotarget.7965. Oncotarget. 2016. PMID: 26967557 Free PMC article.
MG53 nucleates assembly of cell membrane repair machinery.
Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, Hwang M, Ko JK, Lin P, Thornton A, Zhao X, Pan Z, Komazaki S, Brotto M, Takeshima H, Ma J. Cai C, et al. Among authors: lin p. Nat Cell Biol. 2009 Jan;11(1):56-64. doi: 10.1038/ncb1812. Epub 2008 Nov 30. Nat Cell Biol. 2009. PMID: 19043407 Free PMC article.
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy.
Weisleder N, Takizawa N, Lin P, Wang X, Cao C, Zhang Y, Tan T, Ferrante C, Zhu H, Chen PJ, Yan R, Sterling M, Zhao X, Hwang M, Takeshima M, Cai C, Cheng H, Takeshima H, Xiao RP, Ma J. Weisleder N, et al. Among authors: lin p. Sci Transl Med. 2012 Jun 20;4(139):139ra85. doi: 10.1126/scitranslmed.3003921. Sci Transl Med. 2012. PMID: 22723464 Free PMC article.
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling.
Yi JS, Park JS, Ham YM, Nguyen N, Lee NR, Hong J, Kim BW, Lee H, Lee CS, Jeong BC, Song HK, Cho H, Kim YK, Lee JS, Park KS, Shin H, Choi I, Lee SH, Park WJ, Park SY, Choi CS, Lin P, Karunasiri M, Tan T, Duann P, Zhu H, Ma J, Ko YG. Yi JS, et al. Among authors: lin p. Nat Commun. 2013;4:2354. doi: 10.1038/ncomms3354. Nat Commun. 2013. PMID: 23965929 Free PMC article.
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