Engelman AN - Search Results

1

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes.

Rasheedi S, Shun MC, Serrao E, Sowd GA, Qian J, Hao C, Dasgupta T, Engelman AN, Skowronski J. Rasheedi S, et al. Among authors: engelman an. J Biol Chem. 2016 May 27;291(22):11809-19. doi: 10.1074/jbc.M116.721647. Epub 2016 Mar 18. J Biol Chem. 2016. PMID: 26994143 Free PMC article.

2

The barrier-to-autointegration protein is a host factor for HIV type 1 integration.

Chen H, Engelman A. Chen H, et al. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15270-4. doi: 10.1073/pnas.95.26.15270. Proc Natl Acad Sci U S A. 1998. PMID: 9860958 Free PMC article.

3

Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome.

Chen H, Wei SQ, Engelman A. Chen H, et al. J Biol Chem. 1999 Jun 11;274(24):17358-64. doi: 10.1074/jbc.274.24.17358. J Biol Chem. 1999. PMID: 10358097 Free article.

4

Both the structure and DNA binding function of the barrier-to-autointegration factor contribute to reconstitution of HIV type 1 integration in vitro.

Harris D, Engelman A. Harris D, et al. J Biol Chem. 2000 Dec 15;275(50):39671-7. doi: 10.1074/jbc.M002626200. J Biol Chem. 2000. PMID: 11005805 Free article.

5

Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75.

Maertens G, Cherepanov P, Debyser Z, Engelborghs Y, Engelman A. Maertens G, et al. J Biol Chem. 2004 Aug 6;279(32):33421-9. doi: 10.1074/jbc.M404700200. Epub 2004 May 25. J Biol Chem. 2004. PMID: 15163664 Free article.

6

Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein.

Shun MC, Daigle JE, Vandegraaff N, Engelman A. Shun MC, et al. J Virol. 2007 Jan;81(1):166-72. doi: 10.1128/JVI.01953-06. Epub 2006 Oct 11. J Virol. 2007. PMID: 17035312 Free PMC article.

7

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration.

Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, Kellam P, Cherepanov P, Engelman A. Shun MC, et al. Genes Dev. 2007 Jul 15;21(14):1767-78. doi: 10.1101/gad.1565107. Genes Dev. 2007. PMID: 17639082 Free PMC article.

8

Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding.

Zhao Z, McKee CJ, Kessl JJ, Santos WL, Daigle JE, Engelman A, Verdine G, Kvaratskhelia M. Zhao Z, et al. J Biol Chem. 2008 Feb 29;283(9):5632-41. doi: 10.1074/jbc.M705241200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093980 Free PMC article.

9

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

Shun MC, Botbol Y, Li X, Di Nunzio F, Daigle JE, Yan N, Lieberman J, Lavigne M, Engelman A. Shun MC, et al. J Virol. 2008 Dec;82(23):11555-67. doi: 10.1128/JVI.01561-08. Epub 2008 Sep 17. J Virol. 2008. PMID: 18799576 Free PMC article.

10

Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein.

McKee CJ, Kessl JJ, Shkriabai N, Dar MJ, Engelman A, Kvaratskhelia M. McKee CJ, et al. J Biol Chem. 2008 Nov 14;283(46):31802-12. doi: 10.1074/jbc.M805843200. Epub 2008 Sep 18. J Biol Chem. 2008. PMID: 18801737 Free PMC article.

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