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Assembly and specific recognition of k29- and k33-linked polyubiquitin.
Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D. Michel MA, et al. Among authors: pruneda jn. Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5. Mol Cell. 2015. PMID: 25752577 Free PMC article.
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Mulder MP, Witting K, Berlin I, Pruneda JN, Wu KP, Chang JG, Merkx R, Bialas J, Groettrup M, Vertegaal AC, Schulman BA, Komander D, Neefjes J, El Oualid F, Ovaa H. Mulder MP, et al. Among authors: pruneda jn. Nat Chem Biol. 2016 Jul;12(7):523-30. doi: 10.1038/nchembio.2084. Epub 2016 May 16. Nat Chem Biol. 2016. PMID: 27182664 Free PMC article.
The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence.
Grabe GJ, Zhang Y, Przydacz M, Rolhion N, Yang Y, Pruneda JN, Komander D, Holden DW, Hare SA. Grabe GJ, et al. Among authors: pruneda jn. J Biol Chem. 2016 Dec 9;291(50):25853-25863. doi: 10.1074/jbc.M116.752782. Epub 2016 Oct 27. J Biol Chem. 2016. PMID: 27789710 Free PMC article.
Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Swatek KN, Aumayr M, Pruneda JN, Visser LJ, Berryman S, Kueck AF, Geurink PP, Ovaa H, van Kuppeveld FJM, Tuthill TJ, Skern T, Komander D. Swatek KN, et al. Among authors: pruneda jn. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2371-2376. doi: 10.1073/pnas.1710617115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463763 Free PMC article.
49 results