Cummins TR - Search Results

1

Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration.

Ohlemacher SK, Sridhar A, Xiao Y, Hochstetler AE, Sarfarazi M, Cummins TR, Meyer JS. Ohlemacher SK, et al. Among authors: cummins tr. Stem Cells. 2016 Jun;34(6):1553-62. doi: 10.1002/stem.2356. Epub 2016 Mar 21. Stem Cells. 2016. PMID: 26996528 Free PMC article.

2

Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells.

VanderWall KB, Vij R, Ohlemacher SK, Sridhar A, Fligor CM, Feder EM, Edler MC, Baucum AJ 2nd, Cummins TR, Meyer JS. VanderWall KB, et al. Among authors: cummins tr. Stem Cell Reports. 2019 Feb 12;12(2):201-212. doi: 10.1016/j.stemcr.2018.12.010. Epub 2019 Jan 10. Stem Cell Reports. 2019. PMID: 30639213 Free PMC article.

3

Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells.

Gomes C, VanderWall KB, Pan Y, Lu X, Lavekar SS, Huang KC, Fligor CM, Harkin J, Zhang C, Cummins TR, Meyer JS. Gomes C, et al. Among authors: cummins tr. Stem Cell Reports. 2022 Jul 12;17(7):1636-1649. doi: 10.1016/j.stemcr.2022.05.006. Epub 2022 Jun 16. Stem Cell Reports. 2022. PMID: 35714595 Free PMC article.

4

Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids.

VanderWall KB, Huang KC, Pan Y, Lavekar SS, Fligor CM, Allsop AR, Lentsch KA, Dang P, Zhang C, Tseng HC, Cummins TR, Meyer JS. VanderWall KB, et al. Among authors: cummins tr. Stem Cell Reports. 2020 Jul 14;15(1):52-66. doi: 10.1016/j.stemcr.2020.05.009. Epub 2020 Jun 11. Stem Cell Reports. 2020. PMID: 32531194 Free PMC article.

5

Energy Metabolism and Mitochondrial Superoxide Anion Production in Pre-symptomatic Striatal Neurons Derived from Human-Induced Pluripotent Stem Cells Expressing Mutant Huntingtin.

Hamilton J, Brustovetsky T, Sridhar A, Pan Y, Cummins TR, Meyer JS, Brustovetsky N. Hamilton J, et al. Among authors: cummins tr. Mol Neurobiol. 2020 Feb;57(2):668-684. doi: 10.1007/s12035-019-01734-2. Epub 2019 Aug 21. Mol Neurobiol. 2020. PMID: 31435904

6

Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV.

Xiao Y, Jackson JO 2nd, Liang S, Cummins TR. Xiao Y, et al. Among authors: cummins tr. J Biol Chem. 2011 Aug 5;286(31):27301-10. doi: 10.1074/jbc.M111.246876. Epub 2011 Jun 9. J Biol Chem. 2011. PMID: 21659528 Free PMC article.

7

Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins.

Xiao Y, Blumenthal K, Cummins TR. Xiao Y, et al. Among authors: cummins tr. Mol Pharmacol. 2014 Aug;86(2):159-67. doi: 10.1124/mol.114.092338. Epub 2014 Jun 4. Mol Pharmacol. 2014. PMID: 24898004 Free PMC article.

8

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

Patel RR, Barbosa C, Xiao Y, Cummins TR. Patel RR, et al. Among authors: cummins tr. PLoS One. 2015 Jul 16;10(7):e0133485. doi: 10.1371/journal.pone.0133485. eCollection 2015. PLoS One. 2015. PMID: 26182346 Free PMC article.

9

S-Palmitoylation of the sodium channel Nav1.6 regulates its activity and neuronal excitability.

Pan Y, Xiao Y, Pei Z, Cummins TR. Pan Y, et al. Among authors: cummins tr. J Biol Chem. 2020 May 1;295(18):6151-6164. doi: 10.1074/jbc.RA119.012423. Epub 2020 Mar 11. J Biol Chem. 2020. PMID: 32161114 Free PMC article.

10

Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.

Jarecki BW, Sheets PL, Xiao Y, Jackson JO 2nd, Cummins TR. Jarecki BW, et al. Among authors: cummins tr. Channels (Austin). 2009 Jul-Aug;3(4):259-67. doi: 10.4161/chan.3.4.9341. Epub 2009 Jul 23. Channels (Austin). 2009. PMID: 19633428 Free PMC article.

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