Dou Y - Search Results

1

MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency.

Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. Zhang H, et al. Among authors: dou y. Cell Stem Cell. 2016 Apr 7;18(4):481-94. doi: 10.1016/j.stem.2016.02.004. Epub 2016 Mar 17. Cell Stem Cell. 2016. PMID: 26996599 Free PMC article.

2

Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.

Karatas H, Townsend EC, Bernard D, Dou Y, Wang S. Karatas H, et al. Among authors: dou y. J Med Chem. 2010 Jul 22;53(14):5179-85. doi: 10.1021/jm100139b. J Med Chem. 2010. PMID: 20575550 Free PMC article.

3

An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.

Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y. Cao F, et al. Among authors: dou y. PLoS One. 2010 Nov 23;5(11):e14102. doi: 10.1371/journal.pone.0014102. PLoS One. 2010. PMID: 21124902 Free PMC article.

4

High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.

Karatas H, Townsend EC, Cao F, Chen Y, Bernard D, Liu L, Lei M, Dou Y, Wang S. Karatas H, et al. Among authors: dou y. J Am Chem Soc. 2013 Jan 16;135(2):669-82. doi: 10.1021/ja306028q. Epub 2012 Dec 27. J Am Chem Soc. 2013. PMID: 23210835 Free PMC article.

5

H2A.Z sets the stage in ESCs.

Pandey R, Dou Y. Pandey R, et al. Among authors: dou y. Cell Stem Cell. 2013 Feb 7;12(2):143-4. doi: 10.1016/j.stem.2013.01.012. Cell Stem Cell. 2013. PMID: 23395439 Free article.

6

ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes.

Wu L, Lee SY, Zhou B, Nguyen UT, Muir TW, Tan S, Dou Y. Wu L, et al. Among authors: dou y. Mol Cell. 2013 Mar 28;49(6):1108-20. doi: 10.1016/j.molcel.2013.01.033. Epub 2013 Feb 28. Mol Cell. 2013. PMID: 23453805 Free PMC article.

7

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: dou y. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.

8

H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb.

Wu L, Li L, Zhou B, Qin Z, Dou Y. Wu L, et al. Among authors: dou y. Mol Cell. 2014 Jun 19;54(6):920-931. doi: 10.1016/j.molcel.2014.04.013. Epub 2014 May 15. Mol Cell. 2014. PMID: 24837678 Free PMC article.

9

Hijacked in cancer: the KMT2 (MLL) family of methyltransferases.

Rao RC, Dou Y. Rao RC, et al. Among authors: dou y. Nat Rev Cancer. 2015 Jun;15(6):334-46. doi: 10.1038/nrc3929. Nat Rev Cancer. 2015. PMID: 25998713 Free PMC article. Review.

10

Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma.

Khan M, Walters LL, Li Q, Thomas DG, Miller JM, Zhang Q, Sciallis AP, Liu Y, Dlouhy BJ, Fort PE, Archer SM, Demirci H, Dou Y, Rao RC. Khan M, et al. Among authors: dou y. Lab Invest. 2015 Nov;95(11):1278-90. doi: 10.1038/labinvest.2015.104. Epub 2015 Aug 17. Lab Invest. 2015. PMID: 26280220 Free PMC article.

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