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Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD).
Barroso J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J, Klaric M, Mewes KR, Millet M, Templier M, McNamee P. Barroso J, et al. Among authors: de smedt a. Arch Toxicol. 2017 Feb;91(2):521-547. doi: 10.1007/s00204-016-1679-x. Epub 2016 Mar 21. Arch Toxicol. 2017. PMID: 26997338 Free PMC article. Review.
Cosmetics Europe multi-laboratory pre-validation of the EpiOcular™ reconstituted human tissue test method for the prediction of eye irritation.
Pfannenbecker U, Bessou-Touya S, Faller C, Harbell J, Jacob T, Raabe H, Tailhardat M, Alépée N, De Smedt A, De Wever B, Jones P, Kaluzhny Y, Le Varlet B, McNamee P, Marrec-Fairley M, Van Goethem F. Pfannenbecker U, et al. Among authors: de wever b, de smedt a. Toxicol In Vitro. 2013 Mar;27(2):619-26. doi: 10.1016/j.tiv.2012.11.007. Epub 2012 Nov 16. Toxicol In Vitro. 2013. PMID: 23159500
Cosmetics Europe multi-laboratory pre-validation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritation.
Alépée N, Bessou-Touya S, Cotovio J, de Smedt A, de Wever B, Faller C, Jones P, Le Varlet B, Marrec-Fairley M, Pfannenbecker U, Tailhardat M, van Goethem F, McNamee P. Alépée N, et al. Among authors: de wever b, de smedt a. Toxicol In Vitro. 2013 Aug;27(5):1476-88. doi: 10.1016/j.tiv.2013.02.009. Epub 2013 Mar 20. Toxicol In Vitro. 2013. PMID: 23524228
Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.
Alépée N, Barroso J, De Smedt A, De Wever B, Hibatallah J, Klaric M, Mewes KR, Millet M, Pfannenbecker U, Tailhardat M, Templier M, McNamee P. Alépée N, et al. Among authors: de wever b, de smedt a. Toxicol In Vitro. 2015 Jun;29(4):741-61. doi: 10.1016/j.tiv.2015.02.005. Epub 2015 Feb 18. Toxicol In Vitro. 2015. PMID: 25701760
Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods.
Adriaens E, Barroso J, Eskes C, Hoffmann S, McNamee P, Alépée N, Bessou-Touya S, De Smedt A, De Wever B, Pfannenbecker U, Tailhardat M, Zuang V. Adriaens E, et al. Among authors: de wever b, de smedt a. Arch Toxicol. 2014 Mar;88(3):701-23. doi: 10.1007/s00204-013-1156-8. Epub 2013 Dec 28. Arch Toxicol. 2014. PMID: 24374802 Free PMC article.
The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop.
Ceridono M, Tellner P, Bauer D, Barroso J, Alépée N, Corvi R, De Smedt A, Fellows MD, Gibbs NK, Heisler E, Jacobs A, Jirova D, Jones D, Kandárová H, Kasper P, Akunda JK, Krul C, Learn D, Liebsch M, Lynch AM, Muster W, Nakamura K, Nash JF, Pfannenbecker U, Phillips G, Robles C, Rogiers V, Van De Water F, Liminga UW, Vohr HW, Wattrelos O, Woods J, Zuang V, Kreysa J, Wilcox P. Ceridono M, et al. Among authors: de smedt a. Regul Toxicol Pharmacol. 2012 Aug;63(3):480-8. doi: 10.1016/j.yrtph.2012.06.001. Epub 2012 Jun 9. Regul Toxicol Pharmacol. 2012. PMID: 22687423
A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure-activity alert spaces.
Canipa SJ, Chilton ML, Hemingway R, Macmillan DS, Myden A, Plante JP, Tennant RE, Vessey JD, Steger-Hartmann T, Gould J, Hillegass J, Etter S, Smith BPC, White A, Sterchele P, De Smedt A, O'Brien D, Parakhia R. Canipa SJ, et al. Among authors: de smedt a. J Appl Toxicol. 2017 Aug;37(8):985-995. doi: 10.1002/jat.3448. Epub 2017 Feb 28. J Appl Toxicol. 2017. PMID: 28244128
111 results