Seagroves TN - Search Results

1

ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.

Brooks DL, Schwab LP, Krutilina R, Parke DN, Sethuraman A, Hoogewijs D, Schörg A, Gotwald L, Fan M, Wenger RH, Seagroves TN. Brooks DL, et al. Among authors: seagroves tn. Mol Cancer. 2016 Mar 22;15:26. doi: 10.1186/s12943-016-0510-x. Mol Cancer. 2016. PMID: 27001172 Free PMC article.

2

Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

Liao D, Corle C, Seagroves TN, Johnson RS. Liao D, et al. Among authors: seagroves tn. Cancer Res. 2007 Jan 15;67(2):563-72. doi: 10.1158/0008-5472.CAN-06-2701. Cancer Res. 2007. PMID: 17234764

3

Dose-dependent modulation of HIF-1alpha/sima controls the rate of cell migration and invasion in Drosophila ovary border cells.

Doronkin S, Djagaeva I, Nagle ME, Reiter LT, Seagroves TN. Doronkin S, et al. Among authors: seagroves tn. Oncogene. 2010 Feb 25;29(8):1123-34. doi: 10.1038/onc.2009.407. Epub 2009 Dec 7. Oncogene. 2010. PMID: 19966858

4

VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis.

Seagroves TN, Peacock DL, Liao D, Schwab LP, Krueger R, Handorf CR, Haase VH, Johnson RS. Seagroves TN, et al. Am J Pathol. 2010 May;176(5):2269-82. doi: 10.2353/ajpath.2010.090310. Epub 2010 Apr 9. Am J Pathol. 2010. PMID: 20382704 Free PMC article.

5

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.

Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, Smith KD, Cushing RC, Seagroves TN. Schwab LP, et al. Among authors: seagroves tn. Breast Cancer Res. 2012 Jan 7;14(1):R6. doi: 10.1186/bcr3087. Breast Cancer Res. 2012. PMID: 22225988 Free PMC article.

6

Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer.

Hallett MA, Teng B, Hasegawa H, Schwab LP, Seagroves TN, Pourmotabbed T. Hallett MA, et al. Among authors: seagroves tn. Breast Cancer Res. 2013 Feb 13;15(1):R12. doi: 10.1186/bcr3385. Breast Cancer Res. 2013. PMID: 23407024 Free PMC article.

7

Chemoprevention activity of dipyridamole in the MMTV-PyMT transgenic mouse model of breast cancer.

Wang C, Schwab LP, Fan M, Seagroves TN, Buolamwini JK. Wang C, et al. Among authors: seagroves tn. Cancer Prev Res (Phila). 2013 May;6(5):437-47. doi: 10.1158/1940-6207.CAPR-12-0345. Epub 2013 Feb 27. Cancer Prev Res (Phila). 2013. PMID: 23447563 Free PMC article.

8

The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance.

Whelan KA, Schwab LP, Karakashev SV, Franchetti L, Johannes GJ, Seagroves TN, Reginato MJ. Whelan KA, et al. Among authors: seagroves tn. J Biol Chem. 2013 May 31;288(22):15865-77. doi: 10.1074/jbc.M112.426999. Epub 2013 Apr 12. J Biol Chem. 2013. PMID: 23585570 Free PMC article.

9

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.

Regan Anderson TM, Peacock DL, Daniel AR, Hubbard GK, Lofgren KA, Girard BJ, Schörg A, Hoogewijs D, Wenger RH, Seagroves TN, Lange CA. Regan Anderson TM, et al. Among authors: seagroves tn. Cancer Res. 2013 Sep 15;73(18):5810-20. doi: 10.1158/0008-5472.CAN-13-0523. Epub 2013 Aug 8. Cancer Res. 2013. PMID: 23928995 Free PMC article.

10

O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway.

Ferrer CM, Lynch TP, Sodi VL, Falcone JN, Schwab LP, Peacock DL, Vocadlo DJ, Seagroves TN, Reginato MJ. Ferrer CM, et al. Among authors: seagroves tn. Mol Cell. 2014 Jun 5;54(5):820-31. doi: 10.1016/j.molcel.2014.04.026. Epub 2014 May 22. Mol Cell. 2014. PMID: 24857547 Free PMC article.

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