Barquinero J - Search Results

1

Long-Term Restoration of Thymidine Phosphorylase Function and Nucleoside Homeostasis Using Hematopoietic Gene Therapy in a Murine Model of Mitochondrial Neurogastrointestinal Encephalomyopathy.

Torres-Torronteras J, Cabrera-Pérez R, Barba I, Costa C, de Luna N, Andreu AL, Barquinero J, Hirano M, Cámara Y, Martí R. Torres-Torronteras J, et al. Among authors: barquinero j. Hum Gene Ther. 2016 Sep;27(9):656-67. doi: 10.1089/hum.2015.160. Epub 2016 May 4. Hum Gene Ther. 2016. PMID: 27004974 Free PMC article.

2

Gene therapy using a liver-targeted AAV vector restores nucleoside and nucleotide homeostasis in a murine model of MNGIE.

Torres-Torronteras J, Viscomi C, Cabrera-Pérez R, Cámara Y, Di Meo I, Barquinero J, Auricchio A, Pizzorno G, Hirano M, Zeviani M, Martí R. Torres-Torronteras J, et al. Among authors: barquinero j. Mol Ther. 2014 May;22(5):901-7. doi: 10.1038/mt.2014.6. Epub 2014 Jan 22. Mol Ther. 2014. PMID: 24448160 Free PMC article.

3

Hematopoietic gene therapy restores thymidine phosphorylase activity in a cell culture and a murine model of MNGIE.

Torres-Torronteras J, Gómez A, Eixarch H, Palenzuela L, Pizzorno G, Hirano M, Andreu AL, Barquinero J, Martí R. Torres-Torronteras J, et al. Among authors: barquinero j. Gene Ther. 2011 Aug;18(8):795-806. doi: 10.1038/gt.2011.24. Epub 2011 Mar 31. Gene Ther. 2011. PMID: 21451581 Free PMC article.

4

Thymidine phosphorylase is both a therapeutic and a suicide gene in a murine model of mitochondrial neurogastrointestinal encephalomyopathy.

López-Estévez S, Ferrer G, Torres-Torronteras J, Mansilla MJ, Casacuberta-Serra S, Martorell L, Hirano M, Martí R, Barquinero J. López-Estévez S, et al. Among authors: barquinero j. Gene Ther. 2014 Jul;21(7):673-81. doi: 10.1038/gt.2014.41. Epub 2014 May 8. Gene Ther. 2014. PMID: 24807807

5

Preclinical Assessment of a Gene-Editing Approach in a Mouse Model of Mitochondrial Neurogastrointestinal Encephalomyopathy.

Parés M, Fornaguera C, Vila-Julià F, Oh S, Fan SHY, Tam YK, Comes N, Vidal F, Martí R, Borrós S, Barquinero J. Parés M, et al. Among authors: barquinero j. Hum Gene Ther. 2021 Oct;32(19-20):1210-1223. doi: 10.1089/hum.2021.152. Hum Gene Ther. 2021. PMID: 34498979

6

Absence of p.R50X Pygm read-through in McArdle disease cellular models.

Tarrasó G, Real-Martinez A, Parés M, Romero-Cortadellas L, Puigros L, Moya L, de Luna N, Brull A, Martín MA, Arenas J, Lucia A, Andreu AL, Barquinero J, Vissing J, Krag TO, Pinós T. Tarrasó G, et al. Among authors: barquinero j. Dis Model Mech. 2020 Jan 13;13(1):dmm043281. doi: 10.1242/dmm.043281. Dis Model Mech. 2020. PMID: 31848135 Free PMC article.

7

Myeloid-derived suppressor cells expressing a self-antigen ameliorate experimental autoimmune encephalomyelitis.

Casacuberta-Serra S, Costa C, Eixarch H, Mansilla MJ, López-Estévez S, Martorell L, Parés M, Montalban X, Espejo C, Barquinero J. Casacuberta-Serra S, et al. Among authors: barquinero j. Exp Neurol. 2016 Dec;286:50-60. doi: 10.1016/j.expneurol.2016.09.012. Epub 2016 Sep 28. Exp Neurol. 2016. PMID: 27693617

8

Myeloablation enhances engraftment of transduced murine hematopoietic cells, but does not influence long-term expression of the transgene.

Puig T, Kádár E, Limón A, Cancelas JA, Eixarch H, Luquín L, García M, Barquinero J. Puig T, et al. Among authors: barquinero j. Gene Ther. 2002 Nov;9(21):1472-9. doi: 10.1038/sj.gt.3301826. Gene Ther. 2002. PMID: 12378410

9

Transgene expression levels determine the immunogenicity of transduced hematopoietic grafts in partially myeloablated mice.

Eixarch H, Gómez A, Kádár E, George M, Martínez N, Espejo C, Pétriz J, Gimeno R, Barquinero J. Eixarch H, et al. Among authors: barquinero j. Mol Ther. 2009 Nov;17(11):1904-9. doi: 10.1038/mt.2009.198. Epub 2009 Aug 25. Mol Ther. 2009. PMID: 19707185 Free PMC article.

10

Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen.

Eixarch H, Espejo C, Gómez A, Mansilla MJ, Castillo M, Mildner A, Vidal F, Gimeno R, Prinz M, Montalban X, Barquinero J. Eixarch H, et al. Among authors: barquinero j. Mol Ther. 2009 May;17(5):897-905. doi: 10.1038/mt.2009.42. Epub 2009 Mar 10. Mol Ther. 2009. PMID: 19277013 Free PMC article.

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