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Page 1
Sfrp1 and Sfrp2 are required for normal male sexual development in mice.
Warr N, Siggers P, Bogani D, Brixey R, Pastorelli L, Yates L, Dean CH, Wells S, Satoh W, Shimono A, Greenfield A. Warr N, et al. Among authors: siggers p. Dev Biol. 2009 Feb 15;326(2):273-84. doi: 10.1016/j.ydbio.2008.11.023. Epub 2008 Dec 7. Dev Biol. 2009. PMID: 19100252 Free article.
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A. Bogani D, et al. Among authors: siggers p. PLoS Biol. 2009 Sep;7(9):e1000196. doi: 10.1371/journal.pbio.1000196. Epub 2009 Sep 15. PLoS Biol. 2009. PMID: 19753101 Free PMC article.
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A. Warr N, et al. Among authors: siggers p. Dev Cell. 2012 Nov 13;23(5):1020-31. doi: 10.1016/j.devcel.2012.09.016. Epub 2012 Oct 25. Dev Cell. 2012. PMID: 23102580 Free PMC article.
Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice.
Warr N, Siggers P, Carré GA, Bogani D, Brixey R, Akiyoshi M, Tachibana M, Teboul L, Wells S, Sanderson J, Greenfield A. Warr N, et al. Among authors: siggers p. Hum Mol Genet. 2014 Jun 1;23(11):3035-44. doi: 10.1093/hmg/ddu020. Epub 2014 Jan 22. Hum Mol Genet. 2014. PMID: 24452333 Free PMC article.
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.
Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stévant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A. Harris A, et al. Among authors: siggers p. Proc Natl Acad Sci U S A. 2018 May 22;115(21):5474-5479. doi: 10.1073/pnas.1801223115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735715 Free PMC article.
28 results