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Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.
Epelman S, Lavine KJ, Beaudin AE, Sojka DK, Carrero JA, Calderon B, Brija T, Gautier EL, Ivanov S, Satpathy AT, Schilling JD, Schwendener R, Sergin I, Razani B, Forsberg EC, Yokoyama WM, Unanue ER, Colonna M, Randolph GJ, Mann DL. Epelman S, et al. Immunity. 2014 Jan 16;40(1):91-104. doi: 10.1016/j.immuni.2013.11.019. Immunity. 2014. PMID: 24439267 Free PMC article.
Origin and functions of tissue macrophages.
Epelman S, Lavine KJ, Randolph GJ. Epelman S, et al. Immunity. 2014 Jul 17;41(1):21-35. doi: 10.1016/j.immuni.2014.06.013. Immunity. 2014. PMID: 25035951 Free PMC article. Review.
Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth.
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS. Ensan S, et al. Among authors: epelman s. Nat Immunol. 2016 Feb;17(2):159-68. doi: 10.1038/ni.3343. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642357
A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis.
Clemente-Casares X, Hosseinzadeh S, Barbu I, Dick SA, Macklin JA, Wang Y, Momen A, Kantores C, Aronoff L, Farno M, Lucas TM, Avery J, Zarrin-Khat D, Elsaesser HJ, Razani B, Lavine KJ, Husain M, Brooks DG, Robbins CS, Cybulsky M, Epelman S. Clemente-Casares X, et al. Among authors: epelman s. Immunity. 2017 Nov 21;47(5):974-989.e8. doi: 10.1016/j.immuni.2017.10.011. Immunity. 2017. PMID: 29166591 Free article.
The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ. Bajpai G, et al. Among authors: epelman s. Nat Med. 2018 Aug;24(8):1234-1245. doi: 10.1038/s41591-018-0059-x. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892064 Free PMC article.
138 results