Moriya Y - Search Results

1

Characterization of Transporters in the Hepatic Uptake of TAK-475 M-I, a Squalene Synthase Inhibitor, in Rats and Humans.

Ebihara T, Takeuchi T, Moriya Y, Tagawa Y, Kondo T, Moriwaki T, Asahi S. Ebihara T, et al. Among authors: moriya y. Drug Res (Stuttg). 2016 Jun;66(6):316-23. doi: 10.1055/s-0035-1569441. Epub 2016 Mar 24. Drug Res (Stuttg). 2016. PMID: 27011383

2

Species differences of organic anion transporters involved in the renal uptake of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of resatorvid, between rats and dogs.

Takeuchi T, Jinno F, Ebihara T, Moriya Y, Kadotani R, Tagawa Y, Kondo T, Itoh T, Asahi S. Takeuchi T, et al. Among authors: moriya y. Biopharm Drug Dispos. 2013 May;34(4):236-46. doi: 10.1002/bdd.1841. Epub 2013 May 7. Biopharm Drug Dispos. 2013. PMID: 23529922

3

Disposition of the Highly Fat Distributed Compound 1-(4-Methoxyphenyl)-4-(2,2,4,6,7-Pentamethyl -2,3-Dihydro-1-Benzofuran-5-yl)Piperazine (TAK-357) in Rats and Dogs.

Goto A, Moriya Y, Mandai T, Wakabayashi T, Tsukamoto T, Tagawa Y, Kondo T, Asahi S. Goto A, et al. Among authors: moriya y. Drug Res (Stuttg). 2017 Jan;67(1):38-45. doi: 10.1055/s-0042-117624. Epub 2016 Oct 11. Drug Res (Stuttg). 2017. PMID: 27728931

4

Pharmacokinetics and Urinary Excretion Mechanism of Orteronel (TAK-700), A Novel 17,20-Lyase Inhibitor, in Animals.

Goto A, Moriya Y, Takeuchi T, Mandai T, Tagawa Y, Kondo T, Asahi S. Goto A, et al. Among authors: moriya y. Drug Res (Stuttg). 2016 Apr;66(4):217-22. doi: 10.1055/s-0035-1564118. Epub 2015 Sep 29. Drug Res (Stuttg). 2016. PMID: 26418412

5

Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Furukawa Y, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: moriya y. Biopharm Drug Dispos. 2017 Sep;38(6):373-380. doi: 10.1002/bdd.2075. Epub 2017 May 23. Biopharm Drug Dispos. 2017. PMID: 28256717

6

Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Yamamoto M, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: moriya y. Biopharm Drug Dispos. 2017 Dec;38(9):543-552. doi: 10.1002/bdd.2106. Epub 2017 Nov 9. Biopharm Drug Dispos. 2017. PMID: 28948605

7

The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S, Benet LZ. Moriya Y, et al. Drug Metab Dispos. 2019 Sep;47(9):1004-1012. doi: 10.1124/dmd.119.087148. Epub 2019 Jun 14. Drug Metab Dispos. 2019. PMID: 31201213

8

Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK-448, for its anti-tumor efficacy in a rat xenograft model.

Kogame A, Ishikawa K, DeJongh J, Tagawa Y, Matsui H, Moriya Y, Kondo T, Asahi S. Kogame A, et al. Among authors: moriya y. Biopharm Drug Dispos. 2020 Jul;41(7):283-294. doi: 10.1002/bdd.2245. Epub 2020 Jul 16. Biopharm Drug Dispos. 2020. PMID: 32562504

9

Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S. Moriya Y, et al. Xenobiotica. 2019 Jul;49(7):833-839. doi: 10.1080/00498254.2018.1499152. Epub 2018 Sep 12. Xenobiotica. 2019. PMID: 30044673

10

Characterization of Fasiglifam-Related Liver Toxicity in Dogs.

Kogame A, Moriya Y, Mori I, Pan L, Morohashi A, Ebihara T, Fukui H, Tagawa Y, Benet LZ. Kogame A, et al. Among authors: moriya y. Drug Metab Dispos. 2019 May;47(5):525-534. doi: 10.1124/dmd.118.084889. Epub 2019 Feb 14. Drug Metab Dispos. 2019. PMID: 30765394

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