Space microgravity drives transdifferentiation of human bone marrow-derived mesenchymal stem cells from osteogenesis to adipogenesis.
Zhang C, Li L, Jiang Y, Wang C, Geng B, Wang Y, Chen J, Liu F, Qiu P, Zhai G, Chen P, Quan R, Wang J.
Zhang C, et al. Among authors: li l.
FASEB J. 2018 Aug;32(8):4444-4458. doi: 10.1096/fj.201700208RR. Epub 2018 Mar 13.
FASEB J. 2018.
PMID: 29533735
Under space microgravity, the increase in p38 MAPK activity and the derepression of AKT activity seem to synchronously lead to the activation of the signaling pathway specifically promoting adipogenesis.-Zhang, C., Li, L., Jiang, Y., Wang, C., Geng, B., Wang, Y., Ch …
Under space microgravity, the increase in p38 MAPK activity and the derepression of AKT activity seem to synchronously lead to the activatio …